(2S)-1-chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol

Base Information

Chemical Name:(2S)-1-chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol
CAS No.:166734-83-4
Molecular Formula:C₇H₁₀ClN₃O₃
Molecular Weight:219.628
Hs Code.:
UNII:H7CGZ9LP53
Nikkaji Number:J3.179.499D
Wikidata:Q105117554
ChEMBL ID:CHEMBL1742294
Mol file:166734-83-4.mol

Synonyms:levornidazole

Suppliers and Price of (2S)-1-chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
OrnidazoleLevo- 98+%
50mg
$ 52.00

ChemScene
OrnidazoleLevo- 99.58%
5mg
$ 55.00

ChemScene
OrnidazoleLevo- 99.58%
50mg
$ 250.00

ChemScene
OrnidazoleLevo- 99.58%
10mg
$ 90.00

AvaChem
Levornidazole
100mg
$ 289.00

AvaChem
Levornidazole
10mg
$ 89.00

Total 29 raw suppliers

Chemical Property of (2S)-1-chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol

Chemical Property:

Boiling Point:443.2 °C at 760 mmHg
PKA:13.29±0.20(Predicted)
Flash Point:221.9 °C
PSA：83.87000
Density:1.53g/cm³
LogP:1.22260
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:219.0410689
Heavy Atom Count:14
Complexity:211

Purity/Quality:

97% ^*data from raw suppliers

OrnidazoleLevo- 98+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=NC=C(N1CC(CCl)O)[N+](=O)[O-]
Isomeric SMILES:CC1=NC=C(N1C[C@@H](CCl)O)[N+](=O)[O-]

Technology Process of (2S)-1-chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol

There total 9 articles about (2S)-1-chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.2%

: 67843-74-7,24969-06-0,13403-37-7
(S)-epichlorohydrin

: 696-23-1,88054-22-2
2-methyl-5-nitro-1H-imidazole

: 16773-42-5,166734-83-4
(S)-(-)-1-(3-chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole

Guidance literature:: With aluminum (III) chloride; In ethyl acetate; at 3 - 5 ℃;

Reference yield: 85.2%

: 696-23-1,88054-22-2
2-methyl-5-nitro-1H-imidazole

: 106-89-8,24969-06-0,13403-37-7
epichlorohydrin

: 16773-42-5,166734-83-4
ornidazole

Guidance literature:: With 1-[3,5-bis(trifluoromethyl)phenyl]-3-[2-(dimethylamino)cyclohexyl]thiourea; In ethyl acetate; at 25 - 30 ℃; for 6h; Solvent; Temperature; Reagent/catalyst;