2-N-acetyl-1-α-allyl-6-O-benzyl-4-deoxy-4-fluoro-muramic acid 2-(phenylsulfonyl)ethyl ester

Base Information

Chemical Name:2-N-acetyl-1-α-allyl-6-O-benzyl-4-deoxy-4-fluoro-muramic acid 2-(phenylsulfonyl)ethyl ester
CAS No.:709669-22-7
Molecular Formula:C₂₉H₃₆FNO₉S
Molecular Weight:593.671
Hs Code.:

Synonyms:2-N-acetyl-1-α-allyl-6-O-benzyl-4-deoxy-4-fluoro-muramic acid 2-(phenylsulfonyl)ethyl ester

Suppliers and Price of 2-N-acetyl-1-α-allyl-6-O-benzyl-4-deoxy-4-fluoro-muramic acid 2-(phenylsulfonyl)ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-N-acetyl-1-α-allyl-6-O-benzyl-4-deoxy-4-fluoro-muramic acid 2-(phenylsulfonyl)ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-N-acetyl-1-α-allyl-6-O-benzyl-4-deoxy-4-fluoro-muramic acid 2-(phenylsulfonyl)ethyl ester

There total 8 articles about 2-N-acetyl-1-α-allyl-6-O-benzyl-4-deoxy-4-fluoro-muramic acid 2-(phenylsulfonyl)ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 20611-21-6
2-(phenylsulfonyl)ethanol

: 709669-21-6
2-N-acetyl-1-α-allyl-6-O-benzyl-4-deoxy-4-fluoro-muramic acid

: 709669-22-7
2-N-acetyl-1-α-allyl-6-O-benzyl-4-deoxy-4-fluoro-muramic acid 2-(phenylsulfonyl)ethyl ester

Guidance literature:: With dmap; 1-methyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 6h;
DOI:10.1021/ol049598w

Reference yield:

: 72-87-7,1136-42-1,1136-44-3,6730-06-9,7772-94-3,10036-64-3,14131-60-3,14131-64-7,14131-68-1,14215-68-0,62057-49-2,62057-50-5,62057-51-6,62057-52-7,62057-53-8,62057-54-9,62057-55-0,62057-56-1,62075-50-7,62137-54-6,134451-97-1,134522-12-6,148347-16-4,6082-29-7
N-acetyl-D-galactosamine

: 709669-22-7
2-N-acetyl-1-α-allyl-6-O-benzyl-4-deoxy-4-fluoro-muramic acid 2-(phenylsulfonyl)ethyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: 80 percent / BF₃*Et₂O / 2 h / 70 °C

2: 75 percent / (+/-)-camphorsulfonic acid / dimethylformamide / 12 h / 20 °C

3: 66 percent / sodium hydride; tetrabutylammonium iodide / tetrahydrofuran / 6 h / 40 °C

4: 81 percent / NaBH₃CN; molecular sieves 4 Angstroem; HCl / tetrahydrofuran; diethyl ether / 1 h / 0 °C

5: 60 percent / (diethylamino)sulfur trifluoride; pyridine / CH₂Cl₂ / -20 - 20 °C

6: 80 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / CH₂Cl₂; H₂O / 4 h / 20 °C

7: 87 percent / sodium hydride / tetrahydrofuran / 18 h / 40 °C

8: 72 percent / 4-(dimethylamino)pyridine; CH₃CH₃N=C=N(CH₂)3N(CH₃)2*HCl / CH₂Cl₂ / 6 h / 20 °C

With pyridine; hydrogenchloride; dmap; 1-methyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; diethylamino-sulfur trifluoride; 4 A molecular sieve; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; tetra-(n-butyl)ammonium iodide; sodium hydride; sodium cyanoborohydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/ol049598w

Reference yield:

: 64650-83-5
N-((2S,3R,4R,5R,6R)-2-Allyloxy-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl)-acetamide

: 709669-22-7
2-N-acetyl-1-α-allyl-6-O-benzyl-4-deoxy-4-fluoro-muramic acid 2-(phenylsulfonyl)ethyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: 75 percent / (+/-)-camphorsulfonic acid / dimethylformamide / 12 h / 20 °C

2: 66 percent / sodium hydride; tetrabutylammonium iodide / tetrahydrofuran / 6 h / 40 °C

3: 81 percent / NaBH₃CN; molecular sieves 4 Angstroem; HCl / tetrahydrofuran; diethyl ether / 1 h / 0 °C

4: 60 percent / (diethylamino)sulfur trifluoride; pyridine / CH₂Cl₂ / -20 - 20 °C

5: 80 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / CH₂Cl₂; H₂O / 4 h / 20 °C

6: 87 percent / sodium hydride / tetrahydrofuran / 18 h / 40 °C

7: 72 percent / 4-(dimethylamino)pyridine; CH₃CH₃N=C=N(CH₂)3N(CH₃)2*HCl / CH₂Cl₂ / 6 h / 20 °C

With pyridine; hydrogenchloride; dmap; 1-methyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; diethylamino-sulfur trifluoride; 4 A molecular sieve; camphor-10-sulfonic acid; tetra-(n-butyl)ammonium iodide; sodium hydride; sodium cyanoborohydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/ol049598w