Boronic acid, [5-(1,1-dimethylethyl)-3-(diphenylphosphino)-2-methoxyphenyl]-

Base Information

Chemical Name:Boronic acid, [5-(1,1-dimethylethyl)-3-(diphenylphosphino)-2-methoxyphenyl]-
CAS No.:171002-45-2
Molecular Formula:C₂₃H₂₆BO₃P
Molecular Weight:392.242
Hs Code.:
DSSTox Substance ID:DTXSID701141997

Synonyms:DTXSID701141997;Boronic acid, [5-(1,1-dimethylethyl)-3-(diphenylphosphino)-2-methoxyphenyl]-;171002-45-2

Suppliers and Price of Boronic acid, [5-(1,1-dimethylethyl)-3-(diphenylphosphino)-2-methoxyphenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Boronic acid, [5-(1,1-dimethylethyl)-3-(diphenylphosphino)-2-methoxyphenyl]-

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:392.1712619
Heavy Atom Count:28
Complexity:451

Purity/Quality:: 95%-98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:B(C1=CC(=CC(=C1OC)P(C2=CC=CC=C2)C3=CC=CC=C3)C(C)(C)C)(O)O

Technology Process of Boronic acid, [5-(1,1-dimethylethyl)-3-(diphenylphosphino)-2-methoxyphenyl]-

There total 1 articles about Boronic acid, [5-(1,1-dimethylethyl)-3-(diphenylphosphino)-2-methoxyphenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 121-43-7,63156-11-6
Trimethyl borate

: 163273-44-7
(3-bromo-5-tert-butyl-2-methoxyphenyl)diphenylphosphine

: 171002-45-2
5-tert-butyl-2-methoxy-3-diphenylphosphinophenyl boronic acid

Guidance literature:: (3-bromo-5-tert-butyl-2-methoxyphenyl)diphenylphosphine; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In diethyl ether; at -78 ℃; for 1h;

Trimethyl borate; at -78 - 20 ℃;

With hydrogenchloride; for 0.5h; pH=2;
DOI:10.1016/S0040-4020(99)00428-7

Reference yield: 82.0%

: 39069-02-8
2,9-dibromo-1,10-phenanthroline

: 171002-45-2
5-tert-butyl-2-methoxy-3-diphenylphosphinophenyl boronic acid

: 2,90bis(5-tert-butyl-3-diphenylphosphino-2-methoxyphenyl)-1,10-phenanthroline

Guidance literature:: With water; sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; toluene; for 12h; Heating;
DOI:10.1016/S0040-4020(99)00428-7

Reference yield:

: 171002-45-2
5-tert-butyl-2-methoxy-3-diphenylphosphinophenyl boronic acid

: 2,90bis(5-tert-butyl-3-diphenylphosphino-2-hydroxyphenyl)-1,10-phenanthroline

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / NaHCO₃; H₂O / Pd(PPh₃)4 / toluene; ethanol / 12 h / Heating

2: BBr₃ / CH₂Cl₂ / -78 - 20 °C

With water; boron tribromide; sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; dichloromethane; toluene; 1: Substitution / 2: Substitution;
DOI:10.1016/S0040-4020(99)00428-7