4'-Chloro-3'-(trifluoromethyl)acetophenone

Base Information

Chemical Name:4'-Chloro-3'-(trifluoromethyl)acetophenone
CAS No.:129825-11-2
Molecular Formula:C9H6ClF3O
Molecular Weight:222.594
Hs Code.:2914700090
European Community (EC) Number:642-454-8
DSSTox Substance ID:DTXSID40378750
Nikkaji Number:J2.883.358J
Wikidata:Q82168305
Mol file:129825-11-2.mol

Synonyms:129825-11-2;4'-Chloro-3'-(trifluoromethyl)acetophenone;4-Chloro-3-(trifluoromethyl)acetophenone;1-[4-chloro-3-(trifluoromethyl)phenyl]ethanone;3'-(trifluoromethyl)-4'-chloroacetophenone;Ethanone, 1-[4-chloro-3-(trifluoromethyl)phenyl]-;1-(4-chloro-3-(trifluoromethyl)phenyl)ethanone;1-[4-chloro-3-(trifluoromethyl)phenyl]ethan-1-one;MFCD03094146;5-Acetyl-2-chlorobenzotrifluoride;Ethanone,1-[4-chloro-3-(trifluoromethyl)phenyl]-;3-(trifluoromethyl)-4-chloroacetophenone;SCHEMBL76697;DTXSID40378750;AKOS015850041;AC-3637;AM61756;CS-W013110;PS-7813;SY032574;C2821;FT-0643117;1-(4-chloro-3-trifluoromethylphenyl)ethanone;4\'-Chloro-3\'-(trifluoromethyl)acetophenone;A19702;EN300-115183;4'-chloro-3'-(trifluoromethyl)acetophenone, AldrichCPR;Z1269124713;4 inverted exclamation mark -Chloro-3 inverted exclamation mark -(trifluoromethyl)acetophenone

Suppliers and Price of 4'-Chloro-3'-(trifluoromethyl)acetophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4''-Chloro-3''-(trifluoromethyl)acetophenone
500mg
$ 75.00

TRC
4''-Chloro-3''-(trifluoromethyl)acetophenone
100mg
$ 60.00

TRC
4''-Chloro-3''-(trifluoromethyl)acetophenone
50mg
$ 45.00

TCI Chemical
4'-Chloro-3'-(trifluoromethyl)acetophenone >98.0%(GC)
5g
$ 90.00

SynQuest Laboratories
4'-Chloro-3'-(trifluoromethyl)acetophenone 98%
250 g
$ 495.00

SynQuest Laboratories
4'-Chloro-3'-(trifluoromethyl)acetophenone 98%
25 g
$ 80.00

SynQuest Laboratories
4'-Chloro-3'-(trifluoromethyl)acetophenone 98%
100 g
$ 255.00

SynQuest Laboratories
4'-Chloro-3'-(trifluoromethyl)acetophenone 98%
5 g
$ 20.00

Sigma-Aldrich
4′-chloro-3′-(trifluoromethyl)acetophenone AldrichCPR
100 mg
$ 57.00

Matrix Scientific
4'-Chloro-3'-(trifluoromethyl)acetophenone 99%
100g
$ 208.00

Total 41 raw suppliers

Chemical Property of 4'-Chloro-3'-(trifluoromethyl)acetophenone

Chemical Property:

Vapor Pressure:0.0469mmHg at 25°C
Melting Point:61-63 °C
Refractive Index:1.466
Boiling Point:236.616 °C at 760 mmHg
Flash Point:96.902 °C
PSA：17.07000
Density:1.337 g/cm³
LogP:3.56140
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:soluble in Methanol
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:222.0059270
Heavy Atom Count:14
Complexity:227

Purity/Quality:

97% ^*data from raw suppliers

4''-Chloro-3''-(trifluoromethyl)acetophenone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi, F
Hazard Codes:Xi,F,Xn
Statements: 22-36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC(=C(C=C1)Cl)C(F)(F)F

Technology Process of 4'-Chloro-3'-(trifluoromethyl)acetophenone

There total 3 articles about 4'-Chloro-3'-(trifluoromethyl)acetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 348-84-5
1-(4-chloro-3-trifluoromethyl-phenyl)-ethanol

: 129825-11-2
1-(4-chloro-3-(trifluoromethyl)phenyl)ethanone

Guidance literature:: With oxalyl dichloride; triethylamine; In dichloromethane; dimethyl sulfoxide; at -78 ℃;

Reference yield:

: 1-Chloro-4-((E)-2-ethoxy-vinyl)-2-trifluoromethyl-benzene

: 129825-11-2
1-(4-chloro-3-(trifluoromethyl)phenyl)ethanone

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; for 3h;
DOI:10.1021/jm049085v

Reference yield:

: 34328-46-6
4-chloro-3-(trifluoromethyl)benzaldehyde

: 129825-11-2
1-(4-chloro-3-(trifluoromethyl)phenyl)ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran; diethyl ether / -78 °C / Inert atmosphere

2: pyridinium chlorochromate / dichloromethane / 20 °C

With pyridinium chlorochromate; In tetrahydrofuran; diethyl ether; dichloromethane;