5-Bromo-4-fluoro-2-methylaniline

Base Information

Chemical Name:5-Bromo-4-fluoro-2-methylaniline
CAS No.:627871-16-3
Molecular Formula:C7H7 Br F N
Molecular Weight:204.042
Hs Code.:2921430090
European Community (EC) Number:624-702-7
DSSTox Substance ID:DTXSID60382293
Wikidata:Q72456133
Mol file:627871-16-3.mol

Synonyms:5-Bromo-4-fluoro-2-methylaniline;627871-16-3;2-Amino-4-bromo-5-fluorotoluene;Benzenamine, 5-bromo-4-fluoro-2-methyl-;MFCD05865218;5-Bromo-4-fluoro-2-methyl-phenylamine;5-bromo-4-fluoro-2-methyl-aniline;2-Amino-4-Bromo-5-Fluorotoluene[5-Bromo-4-Fluoro-2-Methylaniline];2-AMINO-4-BROMO-5-FLUORO-TOLUENE;SCHEMBL249597;DTXSID60382293;DNCLVDGUXUSPTL-UHFFFAOYSA-N;AKOS005064028;AC-3868;AM62054;CS-W003260;PS-8157;5-Bromo-4-fluoro-2-methylaniline, 97%;SY016479;FT-0655750;A19734;EN300-174638

Suppliers and Price of 5-Bromo-4-fluoro-2-methylaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromo-4-fluoro-2-methylaniline
5g
$ 140.00

TRC
5-Bromo-4-fluoro-2-methylaniline
1g
$ 60.00

SynQuest Laboratories
5-Bromo-4-fluoro-2-methylaniline 97%
5 g
$ 110.00

SynQuest Laboratories
5-Bromo-4-fluoro-2-methylaniline 97%
1 g
$ 40.00

SynQuest Laboratories
5-Bromo-4-fluoro-2-methylaniline 97%
10 g
$ 195.00

Sigma-Aldrich
5-Bromo-4-fluoro-2-methylaniline 97%
5g
$ 245.00

Matrix Scientific
5-Bromo-4-fluoro-2-methylaniline 95+%
1g
$ 48.00

Matrix Scientific
5-Bromo-4-fluoro-2-methylaniline 95+%
5g
$ 182.00

Crysdot
5-Bromo-4-fluoro-2-methylaniline 98%
100g
$ 285.00

ChemScene
5-Bromo-4-fluoro-2-methylaniline 99.80%
25g
$ 92.00

Total 59 raw suppliers

Chemical Property of 5-Bromo-4-fluoro-2-methylaniline

Chemical Property:

Vapor Pressure:0.00869mmHg at 25°C
Melting Point:86-90 °C(lit.)
Boiling Point:266.3°C at 760 mmHg
PKA:3.44±0.10(Predicted)
Flash Point:114.9°C
PSA：26.02000
Density:1.589g/cm³
LogP:3.06000
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:202.97459
Heavy Atom Count:10
Complexity:120

Purity/Quality:

98% ^*data from raw suppliers

5-Bromo-4-fluoro-2-methylaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-36/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1N)Br)F

Technology Process of 5-Bromo-4-fluoro-2-methylaniline

There total 2 articles about 5-Bromo-4-fluoro-2-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 224185-19-7
3-bromo-4-fluoro-6-methylnitrobenzene

: 627871-16-3
5-bromo-4-fluoro-2-methylaniline

Guidance literature:: With 2,3-dimethyl-2,3-butane diol; [MoO₂Cl₂(dmf)₂]; In o-xylene; at 130 ℃; for 3h; chemoselective reaction;
DOI:10.1002/adsc.201100877

Reference yield:

: 452-74-4
4-bromo-3-fluorotoluene

: 627871-16-3
5-bromo-4-fluoro-2-methylaniline

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / HNO₃; H₂SO₄ / 0 °C

2: 63 percent / SnCl₂ / ethyl acetate

With sulfuric acid; nitric acid; tin(ll) chloride; In ethyl acetate;
DOI:10.1016/j.bmcl.2005.08.114

Reference yield: 92.0%

: 627871-16-3
5-bromo-4-fluoro-2-methylaniline

: 873922-26-0
5-bromo-4-fluoro-2-methylbenzenethiol

Guidance literature:: 5-bromo-4-fluoro-2-methylaniline; With hydrogenchloride; sodium nitrite;

With potassium ethyl xanthogenate;

With potassium hydroxide; In ethanol;
DOI:10.1016/j.bmcl.2005.08.114