dimethylcarbamic acid 6-chloro-4-methyl-3-{3-(dimethylamino sulfonyl)aminobenzyl}-2-oxo-2H-1-benzopyran-7-yl ester

Base Information

Chemical Name:dimethylcarbamic acid 6-chloro-4-methyl-3-{3-(dimethylamino sulfonyl)aminobenzyl}-2-oxo-2H-1-benzopyran-7-yl ester
CAS No.:946129-48-2
Molecular Formula:C₂₂H₂₄ClN₃O₆S
Molecular Weight:493.968
Hs Code.:

Synonyms:dimethylcarbamic acid 6-chloro-4-methyl-3-{3-(dimethylamino sulfonyl)aminobenzyl}-2-oxo-2H-1-benzopyran-7-yl ester

Suppliers and Price of dimethylcarbamic acid 6-chloro-4-methyl-3-{3-(dimethylamino sulfonyl)aminobenzyl}-2-oxo-2H-1-benzopyran-7-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of dimethylcarbamic acid 6-chloro-4-methyl-3-{3-(dimethylamino sulfonyl)aminobenzyl}-2-oxo-2H-1-benzopyran-7-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of dimethylcarbamic acid 6-chloro-4-methyl-3-{3-(dimethylamino sulfonyl)aminobenzyl}-2-oxo-2H-1-benzopyran-7-yl ester

There total 5 articles about dimethylcarbamic acid 6-chloro-4-methyl-3-{3-(dimethylamino sulfonyl)aminobenzyl}-2-oxo-2H-1-benzopyran-7-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 393810-61-2
dimethylcarbamic acid 2-oxo-2H-3-(3-aminobenzyl)-4-methyl-6-chloro-1-benzopyran-7-yl ester

: 13360-57-1
dimethylamino sulfonyl chloride

: 946129-48-2
dimethylcarbamic acid 6-chloro-4-methyl-3-{3-(dimethylamino sulfonyl)aminobenzyl}-2-oxo-2H-1-benzopyran-7-yl ester

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃; for 24h;

Reference yield:

: 95-88-5
4-Chlororesorcinol

: 946129-48-2
dimethylcarbamic acid 6-chloro-4-methyl-3-{3-(dimethylamino sulfonyl)aminobenzyl}-2-oxo-2H-1-benzopyran-7-yl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: sulfuric acid / water / 12 h / 20 °C

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C / Inert atmosphere

2.2: 5 h / 20 °C / Inert atmosphere

3.1: tin(II) chloride dihdyrate / ethyl acetate / 7 h / 80 °C

4.1: pyridine / dichloromethane / 24 h / 20 °C

With pyridine; tin(II) chloride dihdyrate; sulfuric acid; sodium hydride; In dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; mineral oil; 1.1: |Pechmann Condensation;
DOI:10.1016/j.bmcl.2013.10.001

Reference yield:

: 393812-70-9
2-(3-nitrobenzyl)-3-oxo-butyric acid ethyl ester

: 946129-48-2
dimethylcarbamic acid 6-chloro-4-methyl-3-{3-(dimethylamino sulfonyl)aminobenzyl}-2-oxo-2H-1-benzopyran-7-yl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: sulfuric acid / water / 12 h / 20 °C

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C / Inert atmosphere

2.2: 5 h / 20 °C / Inert atmosphere

3.1: tin(II) chloride dihdyrate / ethyl acetate / 7 h / 80 °C

4.1: pyridine / dichloromethane / 24 h / 20 °C

With pyridine; tin(II) chloride dihdyrate; sulfuric acid; sodium hydride; In dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; mineral oil; 1.1: |Pechmann Condensation;
DOI:10.1016/j.bmcl.2013.10.001