4--5,8-dimethoxyquinoline

Base Information

• Chemical Name: 4--5,8-dimethoxyquinoline
• CAS No.: 126556-52-3
• Molecular Formula: C₁₇H₁₄FNO₅S
• Molecular Weight: 363.366

Synonyms:4--5,8-dimethoxyquinoline

Chemical Property of 4--5,8-dimethoxyquinoline

Chemical Property:

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Technology Process of 4--5,8-dimethoxyquinoline

There total 1 articles about 4--5,8-dimethoxyquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

4-Fluorobenzenesulfonyl chloride (349-88-2) + 5,8-dimethoxy-1H-quinolin-1-one (92264-11-4) → 4--5,8-dimethoxyquinoline (126556-52-3)

Guidance literature:

With 2,6-dimethylpyridine; In dichloromethane; 0 deg C, 1 h; RT, 3 h;

Reference yield: 66.0%

4--5,8-dimethoxyquinoline (126556-52-3) → 4--quinoline-5,8-quinone (126556-59-0)

Guidance literature:

With ammonium cerium(IV) nitrate; In water; acetonitrile; for 0.25h; Ambient temperature;

upstream raw materials:

4-Fluorobenzenesulfonyl chloride

5,8-dimethoxy-1H-quinolin-1-one

Downstream raw materials:

4--quinoline-5,8-quinone

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