Chemical Property of Danusertib
Chemical Property:
- Appearance/Colour:white powder
- Vapor Pressure:0mmHg at 25°C
- Refractive Index:1.663
- Boiling Point:664.149 °C at 760 mmHg
- PKA:13.70±0.20(Predicted)
- Flash Point:355.465 °C
- PSA：93.80000
- Density:1.322 g/cm3
- LogP:2.65750
- Storage Temp.:Refrigerator
- Solubility.:DMSO (Slightly), Methanol (Slightly)
- XLogP3:1.8
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:6
- Rotatable Bond Count:6
- Exact Mass:474.23793884
- Heavy Atom Count:35
- Complexity:731
- Purity/Quality:
-
99%, *data from raw suppliers
Danusertib *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3=NNC4=C3CN(C4)C(=O)C(C5=CC=CC=C5)OC
- Isomeric SMILES:CN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3=NNC4=C3CN(C4)C(=O)[C@@H](C5=CC=CC=C5)OC
- Recent ClinicalTrials:PHA-739358 for Treatment of Hormone Refractory Prostate Cancer
- Recent EU Clinical Trials:A Phase I/II Study of Danusertib in Combination with Romidepsin in Adult Patients with Mature Peripheral T Cell Lymphoma (PTCL)
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Uses
Danusertib is an Aurora kinase inhibitor, used to treat patients with chromic myeloid leukemia. An Aurora kinase inhibitor, used to treat patients with chromic myeloid leukemia. It is a COVID19-related research product.
