R-(+)-4-chloro-1-<4-(1,1-dimethylethyl)phenyl>-1-butanol acetate

Base Information

• Chemical Name: R-(+)-4-chloro-1-<4-(1,1-dimethylethyl)phenyl>-1-butanol acetate
• CAS No.: 151091-48-4
• Molecular Formula: C₁₆H₂₃ClO₂
• Molecular Weight: 282.81
• Mol file: 151091-48-4.mol

Synonyms:R-(+)-4-chloro-1-<4-(1,1-dimethylethyl)phenyl>-1-butanol acetate

Chemical Property of R-(+)-4-chloro-1-<4-(1,1-dimethylethyl)phenyl>-1-butanol acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of R-(+)-4-chloro-1-<4-(1,1-dimethylethyl)phenyl>-1-butanol acetate

There total 5 articles about R-(+)-4-chloro-1-<4-(1,1-dimethylethyl)phenyl>-1-butanol acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

acetyl chloride (75-36-5) + R-(+)-4-chloro-1-<4-(1,1-dimethylethyl)phenyl>-1-butanol (151091-53-1) → R-(+)-4-chloro-1-<4-(1,1-dimethylethyl)phenyl>-1-butanol acetate (151091-48-4)

Guidance literature:

With triethylamine; In diethyl ether; for 2h; Ambient temperature;

DOI:10.1016/0223-5234(93)90009-4

Reference yield: 98.0%

→ R-(+)-4-chloro-1-<4-(1,1-dimethylethyl)phenyl>-1-butanol acetate (151091-48-4)

Guidance literature:

With triethylamine; In diethyl ether; at 20 ℃; for 2h;

Reference yield: 47.0%

Isopropenyl acetate (108-22-5) + 4-chloro-1-(4-tert-butylphenyl)-1-butanol → R-(+)-4-chloro-1-<4-(1,1-dimethylethyl)phenyl>-1-butanol acetate (151091-48-4)

Guidance literature:

With Lipase PS; In n-heptane; for 96h;

DOI:10.1016/0957-4166(95)00187-T

upstream raw materials:

acetyl chloride

R-(+)-4-chloro-1-<4-(1,1-dimethylethyl)phenyl>-1-butanol

vinyl acetate

Isopropenyl acetate

Downstream raw materials:

R-(+)-1-<4-acetoxy-4-<4-(1,1-dimethylethyl)phenyl>butyl>-α,α,-diphenyl-4-piperidinomethanol