3-(2-(((4-chlorophenyl)sulfonyl)amino)ethyl)phenyl 3-pyridyl ketone

Base Information

• Chemical Name: 3-(2-(((4-chlorophenyl)sulfonyl)amino)ethyl)phenyl 3-pyridyl ketone
• CAS No.: 153731-70-5
• Molecular Formula: C₂₀H₁₇ClN₂O₃S
• Molecular Weight: 400.886
• Mol file: 153731-70-5.mol

Synonyms:3-(2-(((4-chlorophenyl)sulfonyl)amino)ethyl)phenyl 3-pyridyl ketone

Chemical Property of 3-(2-(((4-chlorophenyl)sulfonyl)amino)ethyl)phenyl 3-pyridyl ketone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(2-(((4-chlorophenyl)sulfonyl)amino)ethyl)phenyl 3-pyridyl ketone

There total 5 articles about 3-(2-(((4-chlorophenyl)sulfonyl)amino)ethyl)phenyl 3-pyridyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-pyridinecarboxaldehyde (500-22-1) → 3-(2-(((4-chlorophenyl)sulfonyl)amino)ethyl)phenyl 3-pyridyl ketone (153731-70-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) butyllithium / 1.) THF, hexane, -70 deg C, 30 min, 2.) THF, hexane, 2 h

2: MnO₂ / CHCl₃ / 2 h

3: 2 N aq. HCl / 1 h / 25 - 40 °C

4: Et₃N / 1 h

With hydrogenchloride; manganese(IV) oxide; n-butyllithium; triethylamine; In chloroform;

Reference yield:

[2-(3-bromophenyl)ethyl]carbamic acid tert-butyl ester (153732-25-3) → 3-(2-(((4-chlorophenyl)sulfonyl)amino)ethyl)phenyl 3-pyridyl ketone (153731-70-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) butyllithium / 1.) THF, hexane, -70 deg C, 30 min, 2.) THF, hexane, 2 h

2: MnO₂ / CHCl₃ / 2 h

3: 2 N aq. HCl / 1 h / 25 - 40 °C

4: Et₃N / 1 h

With hydrogenchloride; manganese(IV) oxide; n-butyllithium; triethylamine; In chloroform;

Reference yield:

{2-[3-(Hydroxy-pyridin-3-yl-methyl)-phenyl]-ethyl}-carbamic acid tert-butyl ester (1027261-73-9) → 3-(2-(((4-chlorophenyl)sulfonyl)amino)ethyl)phenyl 3-pyridyl ketone (153731-70-5)

Guidance literature:

Multi-step reaction with 3 steps

1: MnO₂ / CHCl₃ / 2 h

2: 2 N aq. HCl / 1 h / 25 - 40 °C

3: Et₃N / 1 h

With hydrogenchloride; manganese(IV) oxide; triethylamine; In chloroform;

upstream raw materials:

4-chlorobenzenesulfonyl chloride

[3-(2-Amino-ethyl)-phenyl]-pyridin-3-yl-methanone

3-pyridinecarboxaldehyde

[2-(3-bromophenyl)ethyl]carbamic acid tert-butyl ester