N-{2-[(5-benzyl-4-phenyl-1,3-thiazol-2-yl)amino]-2-oxoethyl}-3,4-diethoxybenzamide

Base Information

• Chemical Name: N-{2-[(5-benzyl-4-phenyl-1,3-thiazol-2-yl)amino]-2-oxoethyl}-3,4-diethoxybenzamide
• CAS No.: 1240636-66-1
• Molecular Formula: C₂₉H₂₉N₃O₄S
• Molecular Weight: 515.633
• Mol file: 1240636-66-1.mol

Synonyms:N-{2-[(5-benzyl-4-phenyl-1,3-thiazol-2-yl)amino]-2-oxoethyl}-3,4-diethoxybenzamide

Chemical Property of N-{2-[(5-benzyl-4-phenyl-1,3-thiazol-2-yl)amino]-2-oxoethyl}-3,4-diethoxybenzamide

Chemical Property:

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Technology Process of N-{2-[(5-benzyl-4-phenyl-1,3-thiazol-2-yl)amino]-2-oxoethyl}-3,4-diethoxybenzamide

There total 1 articles about N-{2-[(5-benzyl-4-phenyl-1,3-thiazol-2-yl)amino]-2-oxoethyl}-3,4-diethoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

4-phenyl-5-(phenylmethyl)-1,3-thiazol-2-amine (905592-30-5) + N-[(3,4-diethoxyphenyl)carbonyl]glycine (568544-09-2) → N-{2-[(5-benzyl-4-phenyl-1,3-thiazol-2-yl)amino]-2-oxoethyl}-3,4-diethoxybenzamide (1240636-66-1)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In acetonitrile; at 50 ℃; for 4h;

DOI:10.1248/cpb.58.673

upstream raw materials:

4-phenyl-5-(phenylmethyl)-1,3-thiazol-2-amine

N-[(3,4-diethoxyphenyl)carbonyl]glycine

Refernces