568544-09-2Relevant academic research and scientific papers
Novel acyl coenzyme A: Diacylglycerol acyltransferase 1 inhibitors - Synthesis and biological activities of N-(substituted heteroaryl)-4-(substituted phenyl)-4-oxobutanamides
Nakada, Yoshihisa,Ogino, Masaki,Asano, Kouhei,Aoki, Kazuko,Miki, Hiroshi,Yamamoto, Toshihiro,Kato, Koki,Masago, Minori,Tamura, Norikazu,Shimada, Mitsuyuki
experimental part, p. 673 - 679 (2010/08/19)
In a program to discover new small molecule diacylglycerol acyltransferase (DGAT)-1 inhibitors, screening of our in-house chemical library was carried out using recombinant human DGAT-1 enzyme. From this library, the lead compound 1a was identified as a n
