(S)-(-)-1-benzyl-3-(N,N-dibenzylamino)pyrrolidine-2,5-dione

Base Information

• Chemical Name: (S)-(-)-1-benzyl-3-(N,N-dibenzylamino)pyrrolidine-2,5-dione
• CAS No.: 137428-33-2
• Molecular Formula: C₂₅H₂₄N₂O₂
• Molecular Weight: 384.478
• Mol file: 137428-33-2.mol

Synonyms:(S)-(-)-1-benzyl-3-(N,N-dibenzylamino)pyrrolidine-2,5-dione

Chemical Property of (S)-(-)-1-benzyl-3-(N,N-dibenzylamino)pyrrolidine-2,5-dione

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of (S)-(-)-1-benzyl-3-(N,N-dibenzylamino)pyrrolidine-2,5-dione

There total 2 articles about (S)-(-)-1-benzyl-3-(N,N-dibenzylamino)pyrrolidine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

L-asparagine (70-47-3,28088-48-4,7006-34-0) + benzyl bromide (100-39-0) → (S)-(-)-1-benzyl-3-(N,N-dibenzylamino)pyrrolidine-2,5-dione (137428-33-2) + N,N-dibenzylasparaginic acid dibenzyl ester (159497-65-1)

Guidance literature:

With potassium carbonate; In water; for 2h; Heating;

Reference yield: 26.0%

L-asparagine (70-47-3,28088-48-4,7006-34-0) + benzyl bromide (100-39-0) → (S)-(-)-1-benzyl-3-(N,N-dibenzylamino)pyrrolidine-2,5-dione (137428-33-2)

Guidance literature:

With potassium carbonate; In water; for 1h; Heating;

DOI:10.1002/ardp.2503240906

Reference yield: 74.0%

(S)-(-)-1-benzyl-3-(N,N-dibenzylamino)pyrrolidine-2,5-dione (137428-33-2) → (S)-(-)-1-benzyl-3-(N,N-dibenzylamino)pyrrolidin-2-one

Guidance literature:

With borane; In tetrahydrofuran; for 4h; Heating;

upstream raw materials:

L-asparagine

benzyl bromide