Technology Process of (E)-4-Benzenesulfonyl-2-diethylamino-hept-2-enenitrile
There total 5 articles about (E)-4-Benzenesulfonyl-2-diethylamino-hept-2-enenitrile which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 100 percent / AcOH / H2O / 8 h / Heating
2: 96 percent / P4S10, NaHCO3 / 1,2-dimethoxy-ethane / 15 h / 20 °C
3: 1.) (CH3)2SO4 / 1.) 12 h, 50 deg C, acetonitrile; 2.) 15 h, 20 deg C
4: solid potassium hydroxyde, tricaprylmethylammonium chloride / tetrahydrofuran / 2 h / solid-liquid phase-transfer conditions
With
potassium hydroxide; tetraphosphorus decasulfide; Aliquat 336; sodium hydrogencarbonate; acetic acid; dimethyl sulfate;
In
tetrahydrofuran; 1,2-dimethoxyethane; water;
DOI:10.1016/S0040-4039(01)91051-2
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 100 percent / AcOH / H2O / 8 h / Heating
2: 96 percent / P4S10, NaHCO3 / 1,2-dimethoxy-ethane / 15 h / 20 °C
3: 1.) (CH3)2SO4 / 1.) 12 h, 50 deg C, acetonitrile; 2.) 15 h, 20 deg C
4: solid potassium hydroxyde, tricaprylmethylammonium chloride / tetrahydrofuran / 2 h / solid-liquid phase-transfer conditions
With
potassium hydroxide; tetraphosphorus decasulfide; Aliquat 336; sodium hydrogencarbonate; acetic acid; dimethyl sulfate;
In
tetrahydrofuran; 1,2-dimethoxyethane; water;
DOI:10.1016/S0040-4039(01)91051-2
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 96 percent / P4S10, NaHCO3 / 1,2-dimethoxy-ethane / 15 h / 20 °C
2: 1.) (CH3)2SO4 / 1.) 12 h, 50 deg C, acetonitrile; 2.) 15 h, 20 deg C
3: solid potassium hydroxyde, tricaprylmethylammonium chloride / tetrahydrofuran / 2 h / solid-liquid phase-transfer conditions
With
potassium hydroxide; tetraphosphorus decasulfide; Aliquat 336; sodium hydrogencarbonate; dimethyl sulfate;
In
tetrahydrofuran; 1,2-dimethoxyethane;
DOI:10.1016/S0040-4039(01)91051-2
