(2'S,6R)-1-methoxy-2,6-dimethyl-6-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-1,4-cyclohexadiene

Base Information

Chemical Name:(2'S,6R)-1-methoxy-2,6-dimethyl-6-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-1,4-cyclohexadiene
CAS No.:115512-93-1
Molecular Formula:C₁₆H₂₅NO₃
Molecular Weight:279.379
Hs Code.:

Synonyms:(2'S,6R)-1-methoxy-2,6-dimethyl-6-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-1,4-cyclohexadiene

Suppliers and Price of (2'S,6R)-1-methoxy-2,6-dimethyl-6-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-1,4-cyclohexadiene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2'S,6R)-1-methoxy-2,6-dimethyl-6-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-1,4-cyclohexadiene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2'S,6R)-1-methoxy-2,6-dimethyl-6-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-1,4-cyclohexadiene

There total 6 articles about (2'S,6R)-1-methoxy-2,6-dimethyl-6-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-1,4-cyclohexadiene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: (2'S,2R)-2,6-dimethyl-2-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-3-cyclohexen-1-one

: 149-73-5
trimethyl orthoformate

: 115512-93-1
(2'S,6R)-1-methoxy-2,6-dimethyl-6-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-1,4-cyclohexadiene

Guidance literature:: With sulfuric acid; In methanol; for 18h; Ambient temperature;
DOI:10.1021/ja00231a038

Reference yield:

: 115513-20-7
(2R,2'S)-2-methyl-2-[[2'-(methoxymethyl)pyrrolidinyl]carbonyl]-cyclohex-3-en-1-one

: 115512-93-1
(2'S,6R)-1-methoxy-2,6-dimethyl-6-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-1,4-cyclohexadiene

Guidance literature:: Multi-step reaction with 2 steps

1: 1) lithium diisopropylamide / 1) hexane, THF, -78 deg C, 20 min; 2) THF, RT, 1 h

2: 76 percent / conc. sulfuric acid / methanol / 18 h / Ambient temperature

With sulfuric acid; lithium diisopropyl amide; In methanol;
DOI:10.1021/ja00231a038

Reference yield:

: 102069-83-0,207511-15-7
2-methoxy-1-<<2(S)-(hydroxymethyl)pyrrolidinyl>carbonyl>benzene

: 115512-93-1
(2'S,6R)-1-methoxy-2,6-dimethyl-6-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-1,4-cyclohexadiene

Guidance literature:: Multi-step reaction with 5 steps

1: sodium hydride / tetrahydrofuran / 18 h / Heating

2: 1.) potassiun, tert-butyl alcohol, ammonia / 1.) THF, -78 deg C, 2.) THF, -78 deg C, 1 h

3: 87 percent / 10percent hydrochloric acid / methanol / 24 h / Ambient temperature

4: 1) lithium diisopropylamide / 1) hexane, THF, -78 deg C, 20 min; 2) THF, RT, 1 h

5: 76 percent / conc. sulfuric acid / methanol / 18 h / Ambient temperature

With hydrogenchloride; sulfuric acid; ammonia; potassium; sodium hydride; tert-butyl alcohol; lithium diisopropyl amide; In tetrahydrofuran; methanol;
DOI:10.1021/ja00231a038