(R)-N-(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)acetamide

Base Information

Chemical Name:(R)-N-(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)acetamide
CAS No.:1260955-13-2
Molecular Formula:C₁₆H₂₄BNO₃
Molecular Weight:289.182
Hs Code.:

Synonyms:(R)-N-(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)acetamide

Suppliers and Price of (R)-N-(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (R)-N-(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)acetamide

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

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Hazard Codes:

MSDS Files:

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Technology Process of (R)-N-(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)acetamide

There total 8 articles about (R)-N-(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 177750-53-7
N-[(1R)-1-(4-bromophenyl)ethyl]acetamide

: 73183-34-3
bis(pinacol)diborane

: 1260955-13-2
(R)-N-(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)acetamide

Guidance literature:: With potassium acetate; 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; at 150 ℃; for 0.333333h; Microwave irradiation;

Reference yield:

: 1347234-35-8
(R)-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanamine

: 108-24-7
acetic anhydride

: 1260955-13-2
(R)-N-(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)acetamide

Guidance literature:: With pyridine; In ethyl acetate; at 30 ℃; for 12h;
DOI:10.1016/j.tetasy.2013.10.004

Reference yield:

: 149104-90-5
4-acetylphenylboronic acid

: 1260955-13-2
(R)-N-(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 2-aminopropanoic acid; pyridoxal 5'-phosphate; NADP; ammonium formate; Candida boidinii formate dehydrogenase; alanine dehydrogenase; Aspergillus terreus ω-transaminase / aq. phosphate buffer; dimethyl sulfoxide / 24 h / 30 °C / Enzymatic reaction

2: tetrahydrofuran / Heating

3: pyridine / ethyl acetate / 12 h / 30 °C

With pyridine; Candida boidinii formate dehydrogenase; 2-aminopropanoic acid; alanine dehydrogenase; pyridoxal 5'-phosphate; Aspergillus terreus ω-transaminase; ammonium formate; NADP; In tetrahydrofuran; aq. phosphate buffer; dimethyl sulfoxide; ethyl acetate;
DOI:10.1016/j.tetasy.2013.10.004