(1R,3S)-1-amino-3-(4-oct-1-ynyl-phenyl)-cyclopentanecarboxylic acid methyl ester (2R,3R)-2,3-dihydroxy-succinate

Base Information

Chemical Name:(1R,3S)-1-amino-3-(4-oct-1-ynyl-phenyl)-cyclopentanecarboxylic acid methyl ester (2R,3R)-2,3-dihydroxy-succinate
CAS No.:1036386-91-0
Molecular Formula:C₄H₆O₆*C₂₁H₂₉NO₂
Molecular Weight:477.555
Hs Code.:

Synonyms:(1R,3S)-1-amino-3-(4-oct-1-ynyl-phenyl)-cyclopentanecarboxylic acid methyl ester (2R,3R)-2,3-dihydroxy-succinate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,3S)-1-amino-3-(4-oct-1-ynyl-phenyl)-cyclopentanecarboxylic acid methyl ester (2R,3R)-2,3-dihydroxy-succinate

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Technology Process of (1R,3S)-1-amino-3-(4-oct-1-ynyl-phenyl)-cyclopentanecarboxylic acid methyl ester (2R,3R)-2,3-dihydroxy-succinate

There total 1 articles about (1R,3S)-1-amino-3-(4-oct-1-ynyl-phenyl)-cyclopentanecarboxylic acid methyl ester (2R,3R)-2,3-dihydroxy-succinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.6%

: 87-69-4,138508-61-9
L-Tartaric acid

: 629-05-0
n-octyne

: 1036030-21-3
methyl (1R,3S)-amino-3-(4-bromophenyl)cyclopentane-1-carboxylate hydrochloride

: 1036386-91-0
(1R,3S)-1-amino-3-(4-oct-1-ynyl-phenyl)-cyclopentanecarboxylic acid methyl ester (2R,3R)-2,3-dihydroxy-succinate

Guidance literature:: n-octyne; methyl (1R,3S)-amino-3-(4-bromophenyl)cyclopentane-1-carboxylate hydrochloride; With piperidine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triphenylphosphine; In tetrahydrofuran; at 60 ℃; for 36h;

L-Tartaric acid; In methanol;