L-Tartaric acid

Base Information

• Chemical Name: L-Tartaric acid
• CAS No.: 87-69-4
• Deprecated CAS: 1336-18-1,8014-54-8,8059-77-6,1039646-76-8,1334703-49-9,1488329-53-8,2088032-42-0,2411406-12-5,138508-61-9,1039646-76-8,1334703-49-9,8014-54-8,8059-77-6
• Molecular Formula: C4H6O6
• Molecular Weight: 150.088
• Hs Code.: 29181200
• European Community (EC) Number: 201-766-0
• ICSC Number: 0772
• NSC Number: 759609
• UNII: 4J4Z8788N8,W4888I119H
• DSSTox Substance ID: DTXSID8023632
• Nikkaji Number: J31.839F
• Wikipedia: Tartaric acid,Tartaric_acid
• Wikidata: Q18226455
• NCI Thesaurus Code: C47744
• RXCUI: 37578
• Metabolomics Workbench ID: 37519
• ChEMBL ID: CHEMBL1236315
• Mol file: 87-69-4.mol

Synonyms:(R*,R*)-(+-)-2,3-dihydroxybutanedioic acid, monoammonium monosodium salt;aluminum tartrate;ammonium tartrate;calcium tartrate;calcium tartrate tetrahydrate;Mn(III) tartrate;potassium tartrate;seignette salt;sodium ammonium tartrate;sodium potassium tartrate;sodium tartrate;stannous tartrate;tartaric acid;tartaric acid, ((R*,R*)-(+-))-isomer;tartaric acid, (R*,S*)-isomer;tartaric acid, (R-(R*,R*))-isomer;tartaric acid, (S-(R*,R*))-isomer;tartaric acid, ammonium sodium salt, (1:1:1) salt, (R*,R*)-(+-)-isomer;tartaric acid, calcium salt, (R-R*,R*)-isomer;tartaric acid, monoammonium salt, (R-(R*,R*))-isomer;tartrate

Chemical Property of L-Tartaric acid

Chemical Property:

• Appearance/Colour: white crystals
• Vapor Pressure: 4.93E-08mmHg at 25°C
• Melting Point: 170-172 °C(lit.)
• Refractive Index: 12.5 ° (C=5, H2O)
• Boiling Point: 399.3 °C at 760 mmHg
• PKA: 2.98, 4.34(at 25℃)
• Flash Point: 209.4 °C
• PSA: 115.06000
• Density: 1.886 g/cm³
• LogP: -2.12260
• Storage Temp.: Store at RT.
• Solubility.: H2O: soluble1M at 20°C, clear, colorless
• Water Solubility.: 1390 g/L (20 ºC)
• XLogP3: -1.9
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 150.01643791
• Heavy Atom Count: 10
• Complexity: 134

Purity/Quality:

99.5%, ^*data from raw suppliers

L+Tartaric Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38-41
• Safety Statements: 26-36-37/39-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Organic Acids
• Canonical SMILES: C(C(C(=O)O)O)(C(=O)O)O
• Isomeric SMILES: [C@@H]([C@H](C(=O)O)O)(C(=O)O)O
• Recent NIPH Clinical Trials: Unraveling of neural basis of voluntary cough and cough reflex
• Inhalation Risk: Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.
• Effects of Short Term Exposure: Corrosive. The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the aerosol may cause lung oedema. The effects may be delayed. Medical observation is indicated.
• Natural Occurrence: L-Tartaric acid (L-TA) is a weak organic acid found naturally in various fruits, including grapes, tamarind, and citrus fruits.
• Chemical Composition and Properties: L-Tartaric acid is also known as 2,3-dihydroxysuccinic acid. It contains carboxylic acid and hydroxyl groups, making it a versatile compound. It is considered a safe and biodegradable substance.
• Uses in Industries: L-Tartaric acid finds widespread use in brewing, pharmaceutical, and food industries due to its natural sourcing and favorable properties. It serves as a chiral recognition material and has applications in asymmetric catalysis, chiral extraction, chiral chromatography, and electrophoretic separation.
• Sprout Suppressing Agent: L-Tartaric acid demonstrates effectiveness as a sprout-suppressing agent. It exhibits allelopathic activities and plays a role in the synthesis of bioactive molecules and antimicrobial agents.
• Use in Drug Formulations: L-Tartaric acid has been studied as a model drug and coformer in co-amorphous systems and solid dispersions. It is explored for its potential to enhance the solubility of active pharmaceutical ingredients (APIs).

Technology Process of L-Tartaric acid

There total 234 articles about L-Tartaric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-Tartaric acid (87-69-4,138508-61-9) + furan-2,3,5(4H)-trione pyridine (1:1) → DL-tartaric acid (133-37-9,138508-61-9) + tartaric acid (87-69-4,138508-61-9)

Guidance literature:

Reference yield:

water (7732-18-5) + DL-trans-epoxysuccinic acid (141-36-6,3272-11-5,16533-72-5,17015-08-6,17087-75-1,22734-83-4) → DL-tartaric acid (133-37-9,138508-61-9) + tartaric acid (87-69-4,138508-61-9)

Guidance literature:

Product distribution;

Reference yield:

O,O'-sulfinyl-tartaric acid diethyl ester (35506-91-3,133522-25-5) → DL-tartaric acid (133-37-9,138508-61-9) + tartaric acid (87-69-4,138508-61-9)

Guidance literature:

upstream raw materials:

(R,R)-(+)-tartaric acid monoamide

L-Tartaric acid

ethanol

[4,4']bi[1,3]dioxolanyl-5,5'-dione

Downstream raw materials:

L_g-tartaric acid bis-((Ξ)-2-ethyl-hexyl ester)

DL-tartaric acid

L_g-tartaric acid dipentyl ester

di-O-p-toluoyl-L-threaric acid-anhydride

Refernces

• 1、 Hong, Dachao,Kitagawa, Yasutaka,Kon, Yoshihiro,Shimoyama, Yoshihiro,Tamura, Satoru. "A cobalt-substituted Keggin-Type polyoxometalate for catalysis of oxidative aromatic cracking reactions in water". . p. 8042 - 8048. Retrieved 2020/12/28.
• 2、 Ferreira, Marta,Kuzniarska-Biernacka, Iwona,Fonseca, António M.,Neves, Isabel C.,Soares, Olívia S.G.P.,Pereira, Manuel F.R.,Figueiredo, José L.,Parpot, Pier. "Electrochemical oxidation of amoxicillin on carbon nanotubes and carbon nanotube supported metal modified electrodes". . p. 322 - 331. Retrieved 2019/07/10.