benzoic acid 3-[(4-bromo-benzenesulfonyl)-(2-phenyl-2H-pyrazol-3-yl)-amino]-propyl ester

Base Information

• Chemical Name: benzoic acid 3-[(4-bromo-benzenesulfonyl)-(2-phenyl-2H-pyrazol-3-yl)-amino]-propyl ester
• CAS No.: 693790-60-2
• Molecular Formula: C₂₅H₂₂BrN₃O₄S
• Molecular Weight: 540.437
• Mol file: 693790-60-2.mol

Synonyms:benzoic acid 3-[(4-bromo-benzenesulfonyl)-(2-phenyl-2H-pyrazol-3-yl)-amino]-propyl ester

Chemical Property of benzoic acid 3-[(4-bromo-benzenesulfonyl)-(2-phenyl-2H-pyrazol-3-yl)-amino]-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzoic acid 3-[(4-bromo-benzenesulfonyl)-(2-phenyl-2H-pyrazol-3-yl)-amino]-propyl ester

There total 3 articles about benzoic acid 3-[(4-bromo-benzenesulfonyl)-(2-phenyl-2H-pyrazol-3-yl)-amino]-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

3-bromopropyl benzoate (6065-69-6) + 4-bromo-N-(2-phenyl-2H-pyrazol-3-yl)benzenesulfonamide (374632-51-6) → benzoic acid 3-[(4-bromo-benzenesulfonyl)-(2-phenyl-2H-pyrazol-3-yl)-amino]-propyl ester (693790-60-2)

Guidance literature:

With sodium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 16h;

DOI:10.1021/jm010861y

Reference yield:

1-phenylpyrazol-5-amine (826-85-7) → benzoic acid 3-[(4-bromo-benzenesulfonyl)-(2-phenyl-2H-pyrazol-3-yl)-amino]-propyl ester (693790-60-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 61 percent / pyridine

2: 77 percent / Na₂CO₃ / dimethylformamide / 16 h / 80 °C

With pyridine; sodium carbonate; In N,N-dimethyl-formamide;

DOI:10.1021/jm010861y

Reference yield:

4-bromobenzenesulfonyl chloride (98-58-8) → benzoic acid 3-[(4-bromo-benzenesulfonyl)-(2-phenyl-2H-pyrazol-3-yl)-amino]-propyl ester (693790-60-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 61 percent / pyridine

2: 77 percent / Na₂CO₃ / dimethylformamide / 16 h / 80 °C

With pyridine; sodium carbonate; In N,N-dimethyl-formamide;

DOI:10.1021/jm010861y

upstream raw materials:

3-bromopropyl benzoate

4-bromo-N-(2-phenyl-2H-pyrazol-3-yl)benzenesulfonamide

1-phenylpyrazol-5-amine

4-bromobenzenesulfonyl chloride

Downstream raw materials:

4-bromo-N-(3-hydroxy-propyl)-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide