5-{7-[(1S,2R)-2-((17R,18R)-17-methoxy-18-methylhexatriacontyl)cyclopropyl]heptylsulfanyl}-1-phenyl-1H-tetrazole

Base Information

Chemical Name:5-{7-[(1S,2R)-2-((17R,18R)-17-methoxy-18-methylhexatriacontyl)cyclopropyl]heptylsulfanyl}-1-phenyl-1H-tetrazole
CAS No.:934503-18-1
Molecular Formula:C₅₅H₁₀₀N₄OS
Molecular Weight:865.491
Hs Code.:

Synonyms:5-{7-[(1S,2R)-2-((17R,18R)-17-methoxy-18-methylhexatriacontyl)cyclopropyl]heptylsulfanyl}-1-phenyl-1H-tetrazole

Suppliers and Price of 5-{7-[(1S,2R)-2-((17R,18R)-17-methoxy-18-methylhexatriacontyl)cyclopropyl]heptylsulfanyl}-1-phenyl-1H-tetrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-{7-[(1S,2R)-2-((17R,18R)-17-methoxy-18-methylhexatriacontyl)cyclopropyl]heptylsulfanyl}-1-phenyl-1H-tetrazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-{7-[(1S,2R)-2-((17R,18R)-17-methoxy-18-methylhexatriacontyl)cyclopropyl]heptylsulfanyl}-1-phenyl-1H-tetrazole

There total 34 articles about 5-{7-[(1S,2R)-2-((17R,18R)-17-methoxy-18-methylhexatriacontyl)cyclopropyl]heptylsulfanyl}-1-phenyl-1H-tetrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 934503-16-9
(1S,2R)-1-(7-bromoheptyl)-2-((17R,18R)-17-methoxy-18-methylhexatriacontyl)cyclopropane

: 86-93-1
1-Phenyl-1H-tetrazole-5-thiol

: 934503-18-1
5-{7-[(1S,2R)-2-((17R,18R)-17-methoxy-18-methylhexatriacontyl)cyclopropyl]heptylsulfanyl}-1-phenyl-1H-tetrazole

Guidance literature:: With potassium carbonate; In tetrahydrofuran; acetone; at 20 - 40 ℃; for 21h;
DOI:10.1016/j.tet.2007.01.007

Reference yield:

: 943962-72-9
2,2-dimethyl-propionic acid 8-bromooctyl ester

: 934503-18-1
5-{7-[(1S,2R)-2-((17R,18R)-17-methoxy-18-methylhexatriacontyl)cyclopropyl]heptylsulfanyl}-1-phenyl-1H-tetrazole

Guidance literature:: Multi-step reaction with 11 steps

1: 90 percent / potassium carbonate / acetone / 16 h / 20 °C

2: 89 percent / ammonium molybdate(VI) tetrahydrate; aq. hydrogen peroxide / tetrahydrofuran; various solvent(s) / 2 h / 20 °C

3: 91 percent / lithium hexamethyldisilazide / tetrahydrofuran / 16 h / 20 °C

4: 93 percent / hydrogen / palladium on charcoal / ethanol

5: 98 percent / potassium hydroxide / methanol; tetrahydrofuran / 3 h / 40 °C

6: 85 percent / N-bromosuccinimide; triphenylphosphine / CH₂Cl₂ / 1 h / 20 °C

7: 91 percent / potassium carbonate / acetone / 18 h / 20 °C

8: 82 percent / ammonium heptamolybdate(VI) tetrahydrate; aq. hydrogen peroxide / tetrahydrofuran; various solvent(s) / 1 h / 20 °C

9: 74 percent / lithium hexamethyldisilazide / tetrahydrofuran / 2 h / 20 °C

10: 80 percent / 2,4,6-triisopropyl sulfonylhydrazide / tetrahydrofuran / 52 °C

11: 88 percent / potassium carbonate / tetrahydrofuran; acetone / 21 h / 20 - 40 °C

With potassium hydroxide; N-Bromosuccinimide; ammonium molybdate tetrahydrate; ammonium molybdate tetrahydrate; 2,4,6-triisopropyl sulfonylhydrazide; hydrogen; dihydrogen peroxide; potassium carbonate; triphenylphosphine; lithium hexamethyldisilazane; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; dichloromethane; acetone; 3: Julia-Kocienski reaction / 9: Julia-Kocienski reaction;
DOI:10.1016/j.tet.2007.01.007

Reference yield:

: 943962-73-0
2,2-dimethyl propionic acid 8-(1-phenyl-1H-tetrazol-5-yl-sulfanyl)octyl ester

: 934503-18-1
5-{7-[(1S,2R)-2-((17R,18R)-17-methoxy-18-methylhexatriacontyl)cyclopropyl]heptylsulfanyl}-1-phenyl-1H-tetrazole

Guidance literature:: Multi-step reaction with 10 steps

1: 89 percent / ammonium molybdate(VI) tetrahydrate; aq. hydrogen peroxide / tetrahydrofuran; various solvent(s) / 2 h / 20 °C

2: 91 percent / lithium hexamethyldisilazide / tetrahydrofuran / 16 h / 20 °C

3: 93 percent / hydrogen / palladium on charcoal / ethanol

4: 98 percent / potassium hydroxide / methanol; tetrahydrofuran / 3 h / 40 °C

5: 85 percent / N-bromosuccinimide; triphenylphosphine / CH₂Cl₂ / 1 h / 20 °C

6: 91 percent / potassium carbonate / acetone / 18 h / 20 °C

7: 82 percent / ammonium heptamolybdate(VI) tetrahydrate; aq. hydrogen peroxide / tetrahydrofuran; various solvent(s) / 1 h / 20 °C

8: 74 percent / lithium hexamethyldisilazide / tetrahydrofuran / 2 h / 20 °C

9: 80 percent / 2,4,6-triisopropyl sulfonylhydrazide / tetrahydrofuran / 52 °C

10: 88 percent / potassium carbonate / tetrahydrofuran; acetone / 21 h / 20 - 40 °C

With potassium hydroxide; N-Bromosuccinimide; ammonium molybdate tetrahydrate; ammonium molybdate tetrahydrate; 2,4,6-triisopropyl sulfonylhydrazide; hydrogen; dihydrogen peroxide; potassium carbonate; triphenylphosphine; lithium hexamethyldisilazane; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; dichloromethane; acetone; 2: Julia-Kocienski reaction / 8: Julia-Kocienski reaction;
DOI:10.1016/j.tet.2007.01.007