Technology Process of 1-[2-(2,6-diethyl-4-methylphenyl)-2-oxoacetyl]-1-methyl-2-[1-(4-methylphenylsulfonyl)-2-propylidene]hydrazine
There total 11 articles about 1-[2-(2,6-diethyl-4-methylphenyl)-2-oxoacetyl]-1-methyl-2-[1-(4-methylphenylsulfonyl)-2-propylidene]hydrazine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
In
toluene;
at 45 - 60 ℃;
for 7.5h;
under 100 - 120 Torr;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: magnesium; ethylene dibromide / toluene; tetrahydrofuran / 52 h / 40 - 50 °C / Inert atmosphere
1.2: 2 h / 0 - 5 °C / Inert atmosphere
2.1: hydrazine hydrate / methanol / 4.08 h / 1 - 2 °C
3.1: toluene / 2 h / 50 °C / 100 Torr / Inert atmosphere
4.1: potassium carbonate / acetone / 1.5 h / 20 °C / Inert atmosphere
5.1: hydrogen / 5%-palladium/activated carbon / 1,2-dimethoxyethane / 8 h / 20 °C
6.1: toluene / 7.5 h / 45 - 60 °C / 100 - 120 Torr
With
hydrogen; potassium carbonate; hydrazine hydrate; magnesium; ethylene dibromide;
5%-palladium/activated carbon;
In
tetrahydrofuran; methanol; 1,2-dimethoxyethane; acetone; toluene;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: hydrazine hydrate / methanol / 4.08 h / 1 - 2 °C
2: toluene / 2 h / 50 °C / 100 Torr / Inert atmosphere
3: potassium carbonate / toluene / 24 h / 5 °C
4: hydrogen / 5%-palladium/activated carbon / 1,2-dimethoxyethane / 8 h / 20 °C
5: toluene / 7.5 h / 45 - 60 °C / 100 - 120 Torr
With
hydrogen; potassium carbonate; hydrazine hydrate;
5%-palladium/activated carbon;
In
methanol; 1,2-dimethoxyethane; toluene;
