2-benzoyl-4,5-dimethoxyphenylacetic acid

Base Information

• Chemical Name: 2-benzoyl-4,5-dimethoxyphenylacetic acid
• CAS No.: 41148-49-6
• Molecular Formula: C₁₇H₁₆O₅
• Molecular Weight: 300.311
• Mol file: 41148-49-6.mol

Synonyms:2-benzoyl-4,5-dimethoxyphenylacetic acid

Chemical Property of 2-benzoyl-4,5-dimethoxyphenylacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-benzoyl-4,5-dimethoxyphenylacetic acid

There total 10 articles about 2-benzoyl-4,5-dimethoxyphenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

Methyl 2-benzoyl-4,5-dimethoxyphenylacetate (42710-52-1) → 2-benzoyl-4,5-dimethoxyphenylacetic acid (41148-49-6)

Guidance literature:

With sodium hydroxide; In ethanol; for 1h; Heating;

Reference yield: 62.0%

3,4-dihydro-6,7-dimethoxy-1-phenyl-1H-2-benzopyran (22506-58-7) → 2-benzoyl-4,5-dimethoxyphenylacetic acid (41148-49-6)

Guidance literature:

With chromium(VI) oxide; sulfuric acid; In water; acetone; for 2h; Ambient temperature;

Reference yield:

2-(3,4-dimethoxyphenyl)ethyl alcohol (7417-21-2) → 2-benzoyl-4,5-dimethoxyphenylacetic acid (41148-49-6)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl / dioxane / 1 h / Heating

2: CrO₃; H₂SO₄ / acetone; H₂O / 5 °C

With chromium(VI) oxide; hydrogenchloride; sulfuric acid; In 1,4-dioxane; water; acetone;

DOI:10.1016/S0014-827X(01)01186-7

upstream raw materials:

Methyl 2-benzoyl-4,5-dimethoxyphenylacetate

3,4-dihydro-6,7-dimethoxy-1-phenyl-1H-2-benzopyran

(3,4-Dimethoxyphenyl)acetic acid

benzoyl chloride

Downstream raw materials:

6,7-Dimethoxy-1-phenyl-2-benzopyran-3-one

7,8-dimethoxy-1-phenyl-3,5-dihydro-4H-2,3-benzodiazepin-4-one

2,3-Methylbenzodiazepine-2

7,8-dimethoxy-1-phenyl-3,5-dihydro-benzo[d][1,2]diazepine-4-thione