(E/Z)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid Methyl ester

Base Information

Chemical Name:(E/Z)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid Methyl ester
CAS No.:863239-59-2
Molecular Formula:C₂₇H₄₂O₄
Molecular Weight:430.628
Hs Code.:
Mol file:863239-59-2.mol

Synonyms:3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-carboxylic acid methyl ester

Suppliers and Price of (E/Z)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid Methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl(3α,5β)-6-Ethylidene-3-hydroxy-7-oxo-cholan-24-oate
2.5g
$ 205.00

Chemenu
(3alpha,5beta)-6-Ethylidene-3-hydroxy-7-oxocholan-24-oicacidmethylester 97%
10g
$ 468.00

Chemenu
(3alpha,5beta)-6-Ethylidene-3-hydroxy-7-oxocholan-24-oicacidmethylester 97%
5g
$ 281.00

Total 62 raw suppliers

Chemical Property of (E/Z)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid Methyl ester

Chemical Property:

Boiling Point:534.3±43.0 °C(Predicted)
PKA:14.94±0.70(Predicted)
Density:1.104±0.06 g/cm3(Predicted)

Purity/Quality:

99%, ^*data from raw suppliers

Methyl(3α,5β)-6-Ethylidene-3-hydroxy-7-oxo-cholan-24-oate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Methyl (3α,5β)-6-Ethylidene-3-hydroxy-7-oxo-cholan-24-oate is used as a reactant in the preparation of dual agonists of nuclear and membrane bile acid receptors.

Technology Process of (E/Z)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid Methyl ester

There total 9 articles about (E/Z)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid Methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 863239-58-1
3α,7α-bis((trimethylsilyl)oxy)-6-ene-5β-cholanic acid methyl ester

: 75-07-0,9002-91-9
acetaldehyde

: 863239-59-2,1516887-31-2
3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-carboxylic acid methyl ester

Guidance literature:: With boron trifluoride diethyl etherate; In tetrahydrofuran; at -65 - -60 ℃; for 20h; Inert atmosphere;

Reference yield: 77.0%

: 10538-59-7
7-ketolithocholic methyl ester

: 75-07-0,9002-91-9
acetaldehyde

: 863239-59-2,1516887-31-2
3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-carboxylic acid methyl ester

Guidance literature:: 7-ketolithocholic methyl ester; With n-butyllithium; chloro-trimethyl-silane; triethylamine; diisopropylamine; In tetrahydrofuran; at -78 ℃;

acetaldehyde; With boron trifluoride diethyl etherate; In dichloromethane; at -60 ℃;
DOI:10.1021/jm401873d