(3α,5β)-3,7-bis[(trimethylsilyl)oxy]-chol-6-en-4-oic acid methyl ester (BTC-D1) is a synthetic derivative of cholic acid, a primary bile acid. It is known for its potent activation of the farnesoid X receptor (FXR), which is a nuclear receptor that plays a significant role in regulating bile acid metabolism, lipoprotein and glucose homeostasis, and inflammation. BTC-D1 is characterized by its chemical structure that includes two trimethylsilyl ether groups, which provide stability and solubility, making it an effective tool for studying FXR activation and its downstream effects.
863239-58-1
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Basic information
- Product Name: (3α,5β)-3,7-bis[(trimethylsilyl)oxy]-chol-6-en-4-oic acid methyl ester (BTC-D1)
- Synonyms: (3α,5β)-3,7-bis[(trimethylsilyl)oxy]-chol-6-en-4-oic acid methyl ester (BTC-D1)
- CAS NO:863239-58-1
- Molecular Formula:
- Molecular Weight: 548.954
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (3α,5β)-3,7-bis[(trimethylsilyl)oxy]-chol-6-en-4-oic acid methyl ester (BTC-D1)(CAS DataBase Reference)
- NIST Chemistry Reference: (3α,5β)-3,7-bis[(trimethylsilyl)oxy]-chol-6-en-4-oic acid methyl ester (BTC-D1)(863239-58-1)
- EPA Substance Registry System: (3α,5β)-3,7-bis[(trimethylsilyl)oxy]-chol-6-en-4-oic acid methyl ester (BTC-D1)(863239-58-1)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 863239-58-1(Hazardous Substances Data)
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863239-58-1 Usage
Uses
Used in Pharmaceutical Research:BTC-D1 is used as a research compound for studying the physiological and pharmacological roles of the farnesoid X receptor (FXR). Its application is crucial in understanding the potential of FXR as a therapeutic target for the treatment of various metabolic and liver disorders.
Used in Drug Development:
In the pharmaceutical industry, BTC-D1 is utilized as a lead compound in the development of new drugs targeting FXR. Its activation of FXR can potentially lead to the creation of medications that address metabolic and liver diseases.
Used in Metabolic Disorder Treatment:
BTC-D1 is used as a potential therapeutic agent for metabolic disorders due to its ability to activate FXR, which is involved in the regulation of bile acid metabolism, lipoprotein, and glucose homeostasis.
Used in Liver Disease Treatment:
In the medical field, BTC-D1 is explored as a possible treatment for liver disorders, given its influence on FXR, a receptor that plays a role in managing inflammation and other liver-related functions.
Check Digit Verification of cas no
The CAS Registry Mumber 863239-58-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,3,2,3 and 9 respectively; the second part has 2 digits, 5 and 8 respectively.Calculate Digit Verification of CAS Registry Number 863239-58:
(8*8)+(7*6)+(6*3)+(5*2)+(4*3)+(3*9)+(2*5)+(1*8)=191
191 % 10 = 1
So 863239-58-1 is a valid CAS Registry Number.
863239-58-1Upstream product
863239-58-1Downstream Products
- 915038-24-3 (E/Z)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid
- 1516887-31-2 (E)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid methyl ester
- 1516887-31-2 3α-hydroxy-6-ethylidene-7-keto-5β-cholanoic acid-24-methyl ester
- 863239-59-2 3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-carboxylic acid methyl ester
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(3α,5β)-3,7-bis[(trimethylsilyl)oxy]-chol-6-en-4-oic acid methyl ester (BTC-D1)
