Technology Process of C18H14Cl2N6O
There total 7 articles about C18H14Cl2N6O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2,6-dichloro-3-methoxyphenylamine;
With
potassium hexamethylsilazane;
In
tetrahydrofuran; toluene;
at 0 ℃;
for 1h;
C11H8ClN5;
In
tetrahydrofuran; N,N-dimethyl-formamide; toluene;
at 0 - 20 ℃;
for 15h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: hydrogen bromide; acetic acid / 3 h / 40 - 50 °C
2.1: N,N-dimethyl-formamide; trichlorophosphate / 1,2-dichloro-ethane / 3 h / 80 °C
3.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / 1,2-dimethoxyethane; water / 2 h / Inert atmosphere; Reflux
4.1: potassium hexamethylsilazane / tetrahydrofuran; toluene / 1 h / 0 °C
4.2: 15 h / 0 - 20 °C
With
tetrakis(triphenylphosphine) palladium(0); hydrogen bromide; potassium hexamethylsilazane; sodium carbonate; acetic acid; N,N-dimethyl-formamide; trichlorophosphate;
In
tetrahydrofuran; 1,2-dimethoxyethane; water; 1,2-dichloro-ethane; toluene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: N,N-dimethyl-formamide; trichlorophosphate / 1,2-dichloro-ethane / 3 h / 80 °C
2.1: potassium hexamethylsilazane / tetrahydrofuran; toluene / 1 h / 0 °C
2.2: 15 h / 0 - 20 °C
With
potassium hexamethylsilazane; N,N-dimethyl-formamide; trichlorophosphate;
In
tetrahydrofuran; 1,2-dichloro-ethane; toluene;
