2-Bromo-1-pyrazin-2-ylethanone

Base Information

Chemical Name:2-Bromo-1-pyrazin-2-ylethanone
CAS No.:132426-19-8
Molecular Formula:C6H5BrN2O
Molecular Weight:201.023
Hs Code.:2933990090
Mol file:132426-19-8.mol

Synonyms:Ethanone,2-bromo-1-pyrazinyl- (9CI);2-(2-Bromoacetyl)pyrazine;2-(Bromoacetyl)pyrazine;2-Bromo-1-pyrazin-2-ylethanone;

Suppliers and Price of 2-Bromo-1-pyrazin-2-ylethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Bromo-1-(pyrazin-2-yl)ethanone 95+%
1g
$ 680.00

Crysdot
2-Bromo-1-(pyrazin-2-yl)ethanone 95+%
250mg
$ 299.00

Chemenu
2-bromo-1-(pyrazin-2-yl)ethan-1-one 95%
5g
$ 1590.00

Chemenu
2-bromo-1-(pyrazin-2-yl)ethan-1-one 95%
1g
$ 530.00

Biosynth Carbosynth
2-Bromo-1-(2-pyrazinyl) ethanone
500 g
$ 450.00

Biosynth Carbosynth
2-Bromo-1-(2-pyrazinyl) ethanone
250 mg
$ 300.00

Biosynth Carbosynth
2-Bromo-1-(2-pyrazinyl) ethanone
100 mg
$ 220.00

Biosynth Carbosynth
2-Bromo-1-(2-pyrazinyl) ethanone
1 g
$ 600.00

Biosynth Carbosynth
2-Bromo-1-(2-pyrazinyl) ethanone
2 g
$ 1000.00

American Custom Chemicals Corporation
2-BROMO-1-PYRAZIN-2-YL-ETHANONE 95.00%
1G
$ 1963.50

Total 34 raw suppliers

Chemical Property of 2-Bromo-1-pyrazin-2-ylethanone

Chemical Property:

Vapor Pressure:0.007mmHg at 25°C
Refractive Index:1.581
Boiling Point:268.956 °C at 760 mmHg
PKA:-0.91±0.10(Predicted)
Flash Point:116.461 °C
PSA：42.85000
Density:1.667 g/cm³
LogP:1.05420
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-1-(pyrazin-2-yl)ethanone 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-Bromo-1-pyrazin-2-ylethanone used for the synthesis of potent 6-heteroaryl-pyrrolidino-tetrahydroisoquinolines with dual histamine H3 antagonist/serotonin transporter inhibitor activity.

Technology Process of 2-Bromo-1-pyrazin-2-ylethanone

There total 2 articles about 2-Bromo-1-pyrazin-2-ylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22047-25-2
acetylpyrazine

: 132426-19-8
2-bromo-1-(pyrazin-2-yl)ethan-1-one

Guidance literature:: With bromine; In acetic acid; at 50 ℃;
DOI:10.1021/jm9708745

Reference yield:

: 132426-19-8
2-bromo-1-(pyrazin-2-yl)ethan-1-one

Guidance literature:

Reference yield: 54.0%

: 69679-64-7
(1,2-bis(diphenylphosphino)ethane)Ni(SH)2

: 132426-19-8
2-bromo-1-(pyrazin-2-yl)ethan-1-one

: Ni((C₆H₅)2PCH₂CH₂P(C₆H₅)2)(S₂C₂HC₄H₃N₂)*CH₂Cl₂

Guidance literature:: With Et₃N; In N,N-dimethyl-formamide; byproducts: water; N2-atmosphere; treatment od metal complex with bromoketone for 20 min, solvent removal, washing (Et2O), dissoln. in CH2Cl2, dropwise addn. of Et3N to color change to orange red; in air; solvent removal, chromy. (Al2O3, hexane/CH2Cl2=1:2), evapn.; canbe recrystallized (CH2Cl2/pentane); elem. anal.;
DOI:10.1021/ic970194s