1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea.hydrochloride

Base Information

Chemical Name:1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea.hydrochloride
CAS No.:1283526-53-3
Molecular Formula:C₃₁H₃₇N₅O₃*ClH
Molecular Weight:564.127
Hs Code.:

Synonyms:1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea.hydrochloride

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Chemical Property of 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea.hydrochloride

Chemical Property:

Purity/Quality:

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Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea.hydrochloride

There total 6 articles about 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea.hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 285983-48-4
BIRB-796

: 1283526-53-3
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea.hydrochloride

Guidance literature:: With hydrogenchloride; In water;

Reference yield:

: 317806-86-3
3-amino-5-tert-butyl-2-(p-tolyl)-2H-pyrazole hydrochloride

: 1283526-53-3
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea.hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydroxide / ethyl acetate; water / 1 h / 0 °C

1.2: 2 h / 20 °C

2.1: hydrogen / 5%-palladium/activated carbon / dimethyl sulfoxide; tetrahydrofuran; methanol / 20 °C

2.2: 60 °C

3.1: hydrogenchloride / water

With hydrogenchloride; hydrogen; sodium hydroxide; 5%-palladium/activated carbon; In tetrahydrofuran; methanol; water; dimethyl sulfoxide; ethyl acetate;

Reference yield:

: 3647-69-6
4-(2-chloroethyl)morpholine hydrochride

: 1283526-53-3
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea.hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate; sodium hydroxide / 1-methyl-pyrrolidin-2-one / 100 °C

2.1: hydrogen / 5%-palladium/activated carbon / dimethyl sulfoxide; tetrahydrofuran; methanol / 20 °C

2.2: 60 °C

3.1: hydrogenchloride / water

With hydrogenchloride; hydrogen; potassium carbonate; sodium hydroxide; 5%-palladium/activated carbon; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; methanol; water; dimethyl sulfoxide;