4H-Imidazo[4,5-d]pyridazin-4-one, 1,5-dihydro-5-[(phenylmethoxy)methyl]-

Base Information

Chemical Name:4H-Imidazo[4,5-d]pyridazin-4-one, 1,5-dihydro-5-[(phenylmethoxy)methyl]-
CAS No.:82137-50-6
Molecular Formula:C13H12 N4 O2
Molecular Weight:256.264
Hs Code.:
Mol file:82137-50-6.mol

Synonyms:4H-Imidazo[4,5-d]pyridazin-4-one,1,5-dihydro-5-[(phenylmethoxy)methyl]- (9CI); 5-(Benzyloxymethyl)imidazo[4,5-d]pyridazin-4-one

Suppliers and Price of 4H-Imidazo[4,5-d]pyridazin-4-one, 1,5-dihydro-5-[(phenylmethoxy)methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4H-Imidazo[4,5-d]pyridazin-4-one, 1,5-dihydro-5-[(phenylmethoxy)methyl]-

Chemical Property:

PSA：72.80000
LogP:1.29390

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4H-Imidazo[4,5-d]pyridazin-4-one, 1,5-dihydro-5-[(phenylmethoxy)methyl]-

There total 5 articles about 4H-Imidazo[4,5-d]pyridazin-4-one, 1,5-dihydro-5-[(phenylmethoxy)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3587-60-8
Benzyloxymethyl chloride

: 82137-50-6
5-<(benzyloxy)methyl>-1,5-dihydro-4H-imidazo<4,5-d>pyridazin-4-one

Guidance literature:: Multi-step reaction with 5 steps

1: 58 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / dimethylformamide / 2 h

2: 93 percent / NaNO₂ / H₂O; dimethylformamide / 24 h / 80 - 90 °C

3: 80 percent / methanolic ammonia / dimethylformamide / 22 h / 130 °C / a sealed, glass-lined steel bomb

4: 85 percent / H₂ / PtO₂ / ethanol; ethyl acetate / 0.5 h / 1520 Torr / Ambient temperature

5: acetic anhydride / 1 h / Heating

With ammonia; hydrogen; acetic anhydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; sodium nitrite; platinum(IV) oxide; In ethanol; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570210243

Reference yield:

: 92574-75-9
2-((benzyloxy)methyl)-4,5-dichloropyridazin-3(2H)-one

: 82137-50-6
5-<(benzyloxy)methyl>-1,5-dihydro-4H-imidazo<4,5-d>pyridazin-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / NaNO₂ / H₂O; dimethylformamide / 24 h / 80 - 90 °C

2: 80 percent / methanolic ammonia / dimethylformamide / 22 h / 130 °C / a sealed, glass-lined steel bomb

3: 85 percent / H₂ / PtO₂ / ethanol; ethyl acetate / 0.5 h / 1520 Torr / Ambient temperature

4: acetic anhydride / 1 h / Heating

With ammonia; hydrogen; acetic anhydride; sodium nitrite; platinum(IV) oxide; In ethanol; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570210243

Reference yield:

: 92574-76-0
4-hydroxy-5-nitro-2-benzyloxymethylpyridazin-3-one

: 82137-50-6
5-<(benzyloxy)methyl>-1,5-dihydro-4H-imidazo<4,5-d>pyridazin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / methanolic ammonia / dimethylformamide / 22 h / 130 °C / a sealed, glass-lined steel bomb

2: 85 percent / H₂ / PtO₂ / ethanol; ethyl acetate / 0.5 h / 1520 Torr / Ambient temperature

3: acetic anhydride / 1 h / Heating

With ammonia; hydrogen; acetic anhydride; platinum(IV) oxide; In ethanol; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570210243