[tert-butoxycarbonyl-(4-morpholin-4-yl-phenyl)-amino]-propynoic acid methyl ester

Base Information

Chemical Name:[tert-butoxycarbonyl-(4-morpholin-4-yl-phenyl)-amino]-propynoic acid methyl ester
CAS No.:1383718-13-5
Molecular Formula:C₁₉H₂₄N₂O₅
Molecular Weight:360.41
Hs Code.:

Synonyms:[tert-butoxycarbonyl-(4-morpholin-4-yl-phenyl)-amino]-propynoic acid methyl ester

Suppliers and Price of [tert-butoxycarbonyl-(4-morpholin-4-yl-phenyl)-amino]-propynoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [tert-butoxycarbonyl-(4-morpholin-4-yl-phenyl)-amino]-propynoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [tert-butoxycarbonyl-(4-morpholin-4-yl-phenyl)-amino]-propynoic acid methyl ester

There total 1 articles about [tert-butoxycarbonyl-(4-morpholin-4-yl-phenyl)-amino]-propynoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: tert-butyl ethynyl(4-morpholinophenyl)carbamate

: 79-22-1
methyl chloroformate

: 1383718-13-5
[tert-butoxycarbonyl-(4-morpholin-4-yl-phenyl)-amino]-propynoic acid methyl ester

Guidance literature:: tert-butyl ethynyl(4-morpholinophenyl)carbamate; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - -40 ℃; for 1h; Inert atmosphere;

methyl chloroformate; In tetrahydrofuran; at -40 - 20 ℃; Inert atmosphere;

Reference yield: 70.0%

: 1383717-81-4
1,5-bis-benzyloxy-2-isopropyl-4-azido-benzene

: 1383718-13-5
[tert-butoxycarbonyl-(4-morpholin-4-yl-phenyl)-amino]-propynoic acid methyl ester

: 1383718-14-6
1-(2,4-bis-benzyloxy-5-isopropyl-phenyl)-5-[tert-butoxycarbonyl-(4-morpholin-4-yl-phenyl)-amino]-1H-[1,2,3]triazole-4-carboxylic acid methyl ester

Guidance literature:: chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

Reference yield:

: 1383718-13-5
[tert-butoxycarbonyl-(4-morpholin-4-yl-phenyl)-amino]-propynoic acid methyl ester

: 1383718-16-8
[3-(2,4-dihydroxy-5-isopropyl-phenyl)-5-ethylcarbamoyl-3H-[1,2,3]triazol-4-yl]-(4-morpholin-4-yl-phenyl)-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

2: methanol / 24 h / 80 °C / sealed tube

3: hydrogen / 10 wt% Pd(OH)2 on carbon / ethanol / 1 h

With hydrogen; chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer; 10 wt% Pd(OH)2 on carbon; In methanol; ethanol; N,N-dimethyl-formamide;