Technology Process of (S,E)-1-((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)-4,4-dimethylpent-2-enyl carbamate
There total 6 articles about (S,E)-1-((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)-4,4-dimethylpent-2-enyl carbamate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
methanol; water;
at 0 - 23 ℃;
DOI:10.1021/ol053061g
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: tert-butyllithium / diethyl ether; hexane / -78 - 23 °C
1.2: diethyl ether; hexane / 3 h / -78 °C
2.1: 68 percent / N-methylmorpholine N-oxide; tetrapropylammonium perruthenate; molecular sieves 4 Angstroem / CH2Cl2 / 0.58 h / 20 °C
3.1: lithium triethylborohydride / tetrahydrofuran / 0.33 h / -78 °C
4.1: CH2Cl2 / 1 h / 0 °C
5.1: 86 mg / potassium carbonate / methanol; H2O / 0 - 23 °C
With
tetrapropylammonium perruthennate; 4 A molecular sieve; tert.-butyl lithium; lithium triethylborohydride; potassium carbonate; 4-methylmorpholine N-oxide;
In
tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; water;
DOI:10.1021/ol053061g
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: tert-butyllithium / diethyl ether; hexane / -78 - 23 °C
1.2: diethyl ether; hexane / 3 h / -78 °C
2.1: 68 percent / N-methylmorpholine N-oxide; tetrapropylammonium perruthenate; molecular sieves 4 Angstroem / CH2Cl2 / 0.58 h / 20 °C
3.1: lithium triethylborohydride / tetrahydrofuran / 0.33 h / -78 °C
4.1: CH2Cl2 / 1 h / 0 °C
5.1: 86 mg / potassium carbonate / methanol; H2O / 0 - 23 °C
With
tetrapropylammonium perruthennate; 4 A molecular sieve; tert.-butyl lithium; lithium triethylborohydride; potassium carbonate; 4-methylmorpholine N-oxide;
In
tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; water;
DOI:10.1021/ol053061g
