Technology Process of C21H25BrO4
There total 8 articles about C21H25BrO4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane;
at 0 - 25 ℃;
for 14h;
DOI:10.1021/jm400515c
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: boron trifluoride diethyl etherate / dichloromethane / 2 h / -10 °C
2.1: sodium methylate / methanol / 0.5 h / 20 °C
2.2: amberlyte (IR 120 H+) resin
3.1: p-toluenesulfonyl chloride; pyridine / 8 h / 0 - 20 °C
4.1: dimethyl sulfoxide / 4 h / 70 °C
5.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 4 h / 0 - 20 °C
6.1: sodium hydroxide / ethanol / Reflux
6.2: 20 °C
7.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 14 h / 0 - 25 °C
With
pyridine; dmap; boron trifluoride diethyl etherate; sodium methylate; sodium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; p-toluenesulfonyl chloride; sodium hydroxide;
In
methanol; ethanol; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/jm400515c
- Guidance literature:
-
Multi-step reaction with 2 steps
1: iron(III) chloride / dichloromethane / 0 °C
2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 14 h / 0 - 25 °C
With
dmap; iron(III) chloride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane;
DOI:10.1021/jm400515c
