2-(3,4-Dichlorophenyl)-2-oxoethylamine hydrochloride

Base Information

• Chemical Name: 2-(3,4-Dichlorophenyl)-2-oxoethylamine hydrochloride
• CAS No.: 41995-19-1
• Molecular Formula: C8H7Cl2NO^.HCl
• Molecular Weight: 240.517
• Hs Code.: 2922399090
• DSSTox Substance ID: DTXSID20547684
• Mol file: 41995-19-1.mol

Synonyms:41995-19-1;2-(3,4-Dichlorophenyl)-2-oxoethylamine hydrochloride;2-amino-1-(3,4-dichlorophenyl)ethanone hydrochloride;2-amino-1-(3,4-dichlorophenyl)ethan-1-one hydrochloride;MFCD00193094;2-amino-1-(3,4-dichlorophenyl)ethanone;hydrochloride;2-Amino-3',4'-dichloroacetophenone HCl;2-Amino-1-(3,4-dichlorophenyl)ethan-1-one HCl;SCHEMBL745592;DTXSID20547684;IDRFAFYEURFRFD-UHFFFAOYSA-N;AM992;AKOS015890033;SY205114;CS-0215345;2-(3,4-Dichlorophenyl)-2-oxoethylamine HCl;EN300-235775;A825709;F0017-0415;Z1269180328;Ethanone, 2-amino-1-(3,4-dichlorophenyl)-, hydrochloride (1:1);2-Amino-1-(3,4-dichlorophenyl)ethan-1-one--hydrogen chloride (1/1)

Chemical Property of 2-(3,4-Dichlorophenyl)-2-oxoethylamine hydrochloride

Chemical Property:

• Vapor Pressure: 6.83E-06mmHg at 25°C
• Boiling Point: 371.9 °C at 760 mmHg
• Flash Point: 178.7 °C
• PSA: 43.09000
• LogP: 3.63710
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 238.967147
• Heavy Atom Count: 13
• Complexity: 174

Purity/Quality:

98%min ^*data from raw suppliers

2-(3,4-Dichlorophenyl)-2-oxoethylamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1C(=O)CN)Cl)Cl.Cl

Technology Process of 2-(3,4-Dichlorophenyl)-2-oxoethylamine hydrochloride

There total 7 articles about 2-(3,4-Dichlorophenyl)-2-oxoethylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

C14H17Cl2N4O(1+) → 2-amino-1-(3,4-dichloro-phenyl)-ethanone; hydrochloride (41995-19-1)

Guidance literature:

With hydrogenchloride; In ethanol; water; at 20 - 76 ℃;

Reference yield:

2-bromo-1-(3,4-dichlorophenyl)ethanone (2632-10-2) → 2-amino-1-(3,4-dichloro-phenyl)-ethanone; hydrochloride (41995-19-1)

Guidance literature:

2-bromo-1-(3,4-dichlorophenyl)ethanone; With hexamethylenetetramine; sodium iodide; at 20 ℃;

With hydrogenchloride; water; In ethanol; at 76 ℃;

Reference yield:

C10H7Cl2NO3 (875306-52-8) → 2-amino-1-(3,4-dichloro-phenyl)-ethanone; hydrochloride (41995-19-1)

Guidance literature:

With hydrogenchloride; In water; at 125 ℃; for 1h;

upstream raw materials:

(3,4-dichloro-phenacyl)-hexamethylenetetraminium; bromide

C₁₀H₇Cl₂NO₃

2-amino-1-(3,4-dichloro-phenyl)-ethanone

2-bromo-1-(3,4-dichlorophenyl)ethanone

Downstream raw materials:

N-[2-(3,4-dichloro-phenyl)-2-oxo-ethyl]-2-(2,4-dioxo-imidazolidin-1-ylimino)-acetamide

2-(3-([1,2,4]triazolo[1,5-a;]pyridin-6-yl)benzylamino)-1-(3,4-dichlorophenyl)ethanol

Refernces

• 1、 -. "NOVEL ARYL-CYANOGUANIDINE COMPOUNDS". Page/Page column 48. . Retrieved 2016/10/31.
• 2、 -. "ARYL, HETEROARYL, AND HETEROCYCLE SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF". Page/Page column 109-110. . Retrieved 2010/12/17.