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2632-10-2

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2632-10-2 Usage

General Description

3,4-Dichlorophenacyl bromide is a chemical compound used primarily as a reagent for the synthesis of pharmaceuticals and other organic compounds. It is a versatile building block with potential applications in pharmaceuticals, agrochemicals, and materials science. It is commonly utilized as a reagent for the protection of hydroxyl groups in organic synthesis and as an intermediate in the production of various drugs and biologically active compounds. 3,4-Dichlorophenacyl bromide is also used as a mild and selective reagent for the conversion of alcohols to their corresponding bromides, making it a valuable tool for synthetic chemists. Due to its reactivity and potential health hazards, proper safety precautions should be taken when handling and synthesizing this compound.

Check Digit Verification of cas no

The CAS Registry Mumber 2632-10-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,3 and 2 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2632-10:
(6*2)+(5*6)+(4*3)+(3*2)+(2*1)+(1*0)=62
62 % 10 = 2
So 2632-10-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H5BrCl2O/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3H,4H2

2632-10-2 Well-known Company Product Price

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  • Alfa Aesar

  • (A13365)  2-Bromo-3',4'-dichloroacetophenone, 98%   

  • 2632-10-2

  • 5g

  • 386.0CNY

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  • Alfa Aesar

  • (A13365)  2-Bromo-3',4'-dichloroacetophenone, 98%   

  • 2632-10-2

  • 25g

  • 1305.0CNY

  • Detail
  • Alfa Aesar

  • (A13365)  2-Bromo-3',4'-dichloroacetophenone, 98%   

  • 2632-10-2

  • 100g

  • 4438.0CNY

  • Detail

2632-10-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-bromo-1-(3,4-dichlorophenyl)ethanone

1.2 Other means of identification

Product number -
Other names 2-Bromo-1-(3,4-dichlorophenyl)ethanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2632-10-2 SDS

2632-10-2Relevant articles and documents

Anticholinesterase activity screening of some novel dithiocarbamate derivatives including piperidine and piperazine moieties

Levent, Serkan,Acar ?evik, Ulviye,Sa?l?k, Begüm Nurpelin,?zkay, Yusuf,Can, ?zgür Devrim,?zkay, ümide Demir,U?ucu, ümit

, p. 469 - 474 (2017)

The present study was undertaken to synthesize some novel lipophilic piperazine and piperidinedithiocarbamates and investigate their inhibitory potencies against cholinesterase enzymes. In the synthetic studies, 44 new compounds were isolated. The structu

Novel BuChE-IDO1 inhibitors from sertaconazole: Virtual screening, chemical optimization and molecular modeling studies

Zhou, You,Lu, Xin,Du, Chenxi,Liu, Yijun,Wang, Yifan,Hong, Kwon Ho,Chen, Yao,Sun, Haopeng

, (2021/01/07)

In our effort towards the identification of novel BuChE-IDO1 dual-targeted inhibitor for the treatment of Alzheimer's disease (AD), sertaconazole was identified through a combination of structure-based virtual screening followed by MM-GBSA rescoring. Preliminary chemical optimization was performed to develop more potent and selective sertaconazole analogues. In consideration of the selectivity and the inhibitory activity against target proteins, compounds 5c and 5d were selected for the next study. Further modification of compound 5c led to the generation of compound 10g with notably improved selectivity towards BuChE versus AChE. The present study provided us with a good starting point to further design potent and selective BuChE-IDO1 inhibitors, which may benefit the treatment of late stage AD.

Chiral Bidentate Phosphoramidite-Pd Catalyzed Asymmetric Decarboxylative Dipolar Cycloaddition for Multistereogenic Tetrahydrofurans with Cyclic N-Sulfonyl Ketimine Moieties

Lv, Hao-Peng,Yang, Xiao-Peng,Wang, Bai-Lin,Yang, Hao-Di,Wang, Xing-Wang,Wang, Zheng

supporting information, p. 4715 - 4720 (2021/06/28)

An asymmetric [3 + 2] cycloaddition of vinyl ethylenecarbonates (VECs) and (E)-3-arylvinyl substituted benzo[d] isothiazole 1,1-dioxides has been developed using the Pd complex of a bidentate phosphoramidite (Me-BIPAM) as the catalyst, providing a wide variety of chiral multistereogenic vinyltetrahydrofurans in good yields with excellent diastereo- and enantioselectivities (up to >20:1 dr, 99% ee).

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