Technology Process of Methyl N-acetyl-3-phenylisoserine
There total 9 articles about Methyl N-acetyl-3-phenylisoserine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
methanol;
for 48h;
under 760 Torr;
Yield given;
Ambient temperature;
DOI:10.1021/jo00096a072
- Guidance literature:
-
Multi-step reaction with 4 steps
1: p-TsOH / CH2Cl2 / 5 h / Ambient temperature
2: AcBr / CH2Cl2 / 2 h / -15 °C
3: NaN3 / dimethylformamide / 50 °C
4: H2 / 10percent Pd/C / methanol / 48 h / 760 Torr / Ambient temperature
With
sodium azide; Acetyl bromide; hydrogen; toluene-4-sulfonic acid;
palladium on activated charcoal;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo00096a072
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 71 percent / (DHQ)2PHAL, NMO, K2OsO2(OH)4 / H2O; 2-methyl-propan-2-ol / 23 h / Ambient temperature
2: p-TsOH / CH2Cl2 / 5 h / Ambient temperature
3: AcBr / CH2Cl2 / 2 h / -15 °C
4: NaN3 / dimethylformamide / 50 °C
5: H2 / 10percent Pd/C / methanol / 48 h / 760 Torr / Ambient temperature
With
sodium azide; N-methyl-2-indolinone; Hydroquinone 1,4-phthalazinediyl diether; potassium dioxotetrahydroxoosmate(VI); Acetyl bromide; hydrogen; toluene-4-sulfonic acid;
palladium on activated charcoal;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1021/jo00096a072
