Technology Process of 2-hydroxy-6-methyl-4-phenoxy-benzaldehyde
There total 6 articles about 2-hydroxy-6-methyl-4-phenoxy-benzaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
boron tribromide;
In
dichloromethane;
at -78 - 20 ℃;
for 4h;
Cooling with acetone-dry ice;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: copper diacetate / pyridine; dichloromethane; acetonitrile / 20 °C / 4 ? Molecular sieve
2: boron tribromide / dichloromethane / 4 h / -78 - 20 °C / Cooling with acetone-dry ice
With
boron tribromide;
copper diacetate;
In
pyridine; dichloromethane; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: pyridinium p-toluenesulfonate / dichloromethane / 18 h / 20 °C
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.75 h / Cooling with ice
2.2: 1 h / 20 °C
3.1: methanol / Amberlyst.(R). 15 / 1 h / 50 °C
4.1: copper diacetate / pyridine; dichloromethane; acetonitrile / 20 °C / 4 ? Molecular sieve
5.1: boron tribromide / dichloromethane / 4 h / -78 - 20 °C / Cooling with acetone-dry ice
With
methanol; boron tribromide; sodium hydride;
copper diacetate; pyridinium p-toluenesulfonate;
In
pyridine; dichloromethane; N,N-dimethyl-formamide; acetonitrile; mineral oil;
