2-<3-(hydroxymethyl)-5-(2-dimethylamino)ethyl>-4H-1,2,4-triazol-4-yl-5-chloro-benzophenone

Base Information

• Chemical Name: 2-<3-(hydroxymethyl)-5-(2-dimethylamino)ethyl>-4H-1,2,4-triazol-4-yl-5-chloro-benzophenone
• CAS No.: 61955-41-7
• Molecular Formula: C₂₀H₂₁ClN₄O₂
• Molecular Weight: 384.865
• Mol file: 61955-41-7.mol

Synonyms:2-<3-(hydroxymethyl)-5-(2-dimethylamino)ethyl>-4H-1,2,4-triazol-4-yl-5-chloro-benzophenone

Chemical Property of 2-<3-(hydroxymethyl)-5-(2-dimethylamino)ethyl>-4H-1,2,4-triazol-4-yl-5-chloro-benzophenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-<3-(hydroxymethyl)-5-(2-dimethylamino)ethyl>-4H-1,2,4-triazol-4-yl-5-chloro-benzophenone

There total 2 articles about 2-<3-(hydroxymethyl)-5-(2-dimethylamino)ethyl>-4H-1,2,4-triazol-4-yl-5-chloro-benzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-dimethyl(methylene)ammonium chloride (30354-18-8) + 5-chloro-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl] benzophenone (38150-27-5) → 2-<3-(hydroxymethyl)-5-(2-dimethylamino)ethyl>-4H-1,2,4-triazol-4-yl-5-chloro-benzophenone (61955-41-7) + {5-Chloro-2-[3-(1-dimethylaminomethyl-vinyl)-5-hydroxymethyl-[1,2,4]triazol-4-yl]-phenyl}-phenyl-methanone (121899-18-1)

Guidance literature:

In N,N-dimethyl-formamide; at 75 ℃; for 21h;

Reference yield:

→ 2-<3-(hydroxymethyl)-5-(2-dimethylamino)ethyl>-4H-1,2,4-triazol-4-yl-5-chloro-benzophenone (61955-41-7)

Guidance literature:

Reference yield:

phthalimide (136918-14-4,85-41-6) + 2-<3-(hydroxymethyl)-5-(2-dimethylamino)ethyl>-4H-1,2,4-triazol-4-yl-5-chloro-benzophenone (61955-41-7) + diethylazodicarboxylate (1972-28-7,218603-74-8) → 5-Chloro-2-[3-[2-(dimethylamino)ethyl]-5-(phthallmidomethyl)-4H-1,2,4-triazol-4-yl]benzophenone + N-<<4-(2-Benzoyl-4-chlorophenyl)-5-<2-(dimethylamino)ethyl>-4H-1,2,4-triazol-3-yl>methyl>phthalimide (61955-42-8)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran;

upstream raw materials:

N,N-dimethyl(methylene)ammonium chloride

5-chloro-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl] benzophenone

Downstream raw materials:

N-<<4-(2-Benzoyl-4-chlorophenyl)-5-<2-(dimethylamino)ethyl>-4H-1,2,4-triazol-3-yl>methyl>phthalimide