4-cyanobenzyl 2-methoxyacetate

Base Information

• Chemical Name: 4-cyanobenzyl 2-methoxyacetate
• CAS No.: 507250-20-6
• Molecular Formula: C₁₁H₁₁NO₃
• Molecular Weight: 205.213
• Mol file: 507250-20-6.mol

Synonyms:4-cyanobenzyl 2-methoxyacetate

Chemical Property of 4-cyanobenzyl 2-methoxyacetate

Chemical Property:

Purity/Quality:

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Technology Process of 4-cyanobenzyl 2-methoxyacetate

There total 1 articles about 4-cyanobenzyl 2-methoxyacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

4-Cyanobenzyl alcohol (874-89-5) + 2-methoxyacetic acid (625-45-6) → 4-cyanobenzyl 2-methoxyacetate (507250-20-6)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1021/ja410883p

Reference yield: 64.0%

carbon dioxide (124-38-9,18923-20-1) + 4-cyanobenzyl 2-methoxyacetate (507250-20-6) → 4-cyanophenylacetic acid (5462-71-5)

Guidance literature:

With manganese; dichlorobis(trimethylphosphine)nickel; In N,N-dimethyl-formamide; at 100 ℃; for 24h; under 760.051 Torr; Schlenk technique;

DOI:10.1021/ja410883p

upstream raw materials:

4-Cyanobenzyl alcohol

2-methoxyacetic acid

Downstream raw materials:

4-cyanophenylacetic acid

Refernces