625-45-6Relevant articles and documents
Ruthenium Catalyzed Dehydrogenation of Alcohols and Mechanistic Study
Awasthi, Mahendra K.,Singh, Sanjay K.
supporting information, p. 14912 - 14923 (2019/11/03)
We synthesized pyridylamine ligated arene-Ru(II) complexes and employed these complexes for the catalytic acceptorless dehydrogenation of primary alcohols to carboxylic acids. All the synthesized complexes [Ru]-1-[Ru]-10 are characterized using several spectro-analytical techniques, and the structures of complexes [Ru]-1, [Ru]-2, and [Ru]-5 are determined using single crystal X-ray crystallography. Efficient catalytic conversion of primary alcohols to potassium carboxylates or carboxylic acids is achieved in toluene with the quantitative release of hydrogen gas. The studied protocol for carboxylic acid synthesis with hydrogen generation is also employed for a wide range of substrates, including aliphatic alcohols, aromatic alcohols, and heteroaromatic alcohols, to obtain respective carboxylic acids in good yields (up to 86%). The studied arene-Ru catalysts also exhibit superior catalytic activity for the bulk reaction to achieve a turnover number of 1378. Moreover, extensive mass investigations are also performed to elucidate the mechanistic pathway by identifying the crucial catalytic intermediates, including aldehyde and diol coordinated Ru species under the catalytic and controlled reaction conditions.
Synthesis, molecular modeling, and DNA binding of new schiff base ruthenium(II) complex and its catalytic oxidation
El-Shobaky, Amira R.
, p. 1481 - 1488 (2015/06/08)
A new ruthenium(II) complex was derived from 4-aminoantipyrine Schiff base (L). The structural feature has been confirmed through elemental, magnetic susceptibility, and molar conductivity analysis. IR, UV-Vis, and 1H NMR spectral studies show that the complex has composition of [Ru LCl2] type, suggesting an octahedral geometry around the central metal ion. DNA interaction studies throw spectroscopic and viscosity measurement confirmed that complex bind through intercalative mode, which confirmed by computational data throw the calculation of thermodynamic parameter. Also, catalytic oxidation of the Ru(II) complex was carried out showing that the complex is efficient catalyst for the oxidation.
Catalytic transformation of alcohols to carboxylic acid salts and H 2 using water as the oxygen atom source
Balaraman, Ekambaram,Khaskin, Eugene,Leitus, Gregory,Milstein, David
, p. 122 - 125 (2013/08/24)
The oxidation of alcohols to carboxylic acids is an important industrial reaction used in the synthesis of bulk and fine chemicals. Most current processes are performed by making use of either stoichiometric amounts of toxic oxidizing agents or the use of pressurized dioxygen. Here, we describe an alternative dehydrogenative pathway effected by water and base with the concomitant generation of hydrogen gas. A homogeneous ruthenium complex catalyses the transformation of primary alcohols to carboxylic acid salts at low catalyst loadings (0.2 mol%) in basic aqueous solution. A consequence of this finding could be a safer and cleaner process for the synthesis of carboxylic acids and their derivatives at both laboratory and industrial scales.