Z-D-NLE-OH

Base Information

Chemical Name:Z-D-NLE-OH
CAS No.:15027-14-2
Molecular Formula:C14H19NO4
Molecular Weight:265.309
Hs Code.:2924299090
DSSTox Substance ID:DTXSID20426480
Nikkaji Number:J58.656K
Wikidata:Q72442060
Mol file:15027-14-2.mol

Synonyms:D-(Carbobenzyloxy)norleucine;Z-D-Nle-OH;Norleucine,N-carboxy-, N-benzyl ester, D- (8CI);

Suppliers and Price of Z-D-NLE-OH

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Z-D-norleucine
1g
$ 333.00

Crysdot
(R)-2-(((Benzyloxy)carbonyl)amino)hexanoicacid 98%
10g
$ 250.00

Crysdot
(R)-2-(((Benzyloxy)carbonyl)amino)hexanoicacid 98%
5g
$ 140.00

Chem-Impex
Z-D-norleucine,≥99% ≥99%
1G
$ 36.22

Chem-Impex
Z-D-norleucine,99% 99%
5G
$ 151.20

Chem-Impex
Z-D-norleucine,≥99% ≥99%
25G
$ 457.77

Chemenu
(R)-2-(((benzyloxy)carbonyl)amino)hexanoicacid 98%
25g
$ 355.00

Chemenu
(R)-2-(((benzyloxy)carbonyl)amino)hexanoicacid 98%
10g
$ 204.00

American Custom Chemicals Corporation
(2R)-2-(PHENYLMETHOXYCARBONYLAMINO)HEXANOIC ACID 95.00%
250MG
$ 122.10

American Custom Chemicals Corporation
Z-D-NLE-OH 95.00%
1G
$ 217.35

Total 28 raw suppliers

Chemical Property of Z-D-NLE-OH

Chemical Property:

Vapor Pressure:7.43E-09mmHg at 25°C
Melting Point:56-58 °C
Refractive Index:1.528
Boiling Point:449.208 °C at 760 mmHg
PKA:4.00±0.21(Predicted)
Flash Point:225.473 °C
PSA：75.63000
Density:1.161 g/cm³
LogP:2.94710
Storage Temp.:Store at RT.
XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:265.13140809
Heavy Atom Count:19
Complexity:287

Purity/Quality:

97% ^*data from raw suppliers

Z-D-norleucine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC(C(=O)O)NC(=O)OCC1=CC=CC=C1
Isomeric SMILES:CCCC[C@H](C(=O)O)NC(=O)OCC1=CC=CC=C1

Technology Process of Z-D-NLE-OH

There total 14 articles about Z-D-NLE-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 13139-17-8
N-(Benzyloxycarbonyloxy)succinimide

: 327-56-0
D-norleucine

: 15027-14-2
(R)-(((benzyloxy)carbonyl)amino)-D-norleucine

Guidance literature:: With sodium hydrogencarbonate; sodium carbonate; In water; acetone; at 20 ℃; for 12h;
DOI:10.1021/acs.joc.5b01292

Reference yield: 87.0%

: 64-17-5
ethanol

: 15027-13-1
N-benzyloxycarbonylnorleucine

: 15027-14-2
(R)-(((benzyloxy)carbonyl)amino)-D-norleucine

: 117402-84-3,126401-01-2
L-Z-Nor-Leu-OEt

Guidance literature:: With citrate buffer; DL-cysteine hydrochloride; papain; at 50 ℃; for 24h;

Reference yield: 82.0%

: benzyl-((3R)-1,2-dihydroxyheptan-3-yl)carbamate

: 15027-14-2
(R)-(((benzyloxy)carbonyl)amino)-D-norleucine

Guidance literature:: benzyl-((3R)-1,2-dihydroxyheptan-3-yl)carbamate; With sodium periodate; In tetrahydrofuran; water; at 20 ℃; for 2h; Inert atmosphere;

With sodium chlorite; sodium dihydrogenphosphate; In tetrahydrofuran; water; tert-butyl alcohol; at 20 ℃; for 20h; Inert atmosphere;
DOI:10.1002/chem.202002449