H-Lys(Z)-OBzl

Base Information

• Chemical Name: H-Lys(Z)-OBzl
• CAS No.: 24458-14-8
• Molecular Formula: C21H26 N2 O4
• Molecular Weight: 370.448
• Hs Code.: 2924299090
• Mol file: 24458-14-8.mol

Synonyms:Lysine,N6-carboxy-, dibenzyl ester, L- (8CI); Lys(Z)-OBzl;N-e-Carbobenzyloxy-L-lysine benzyl ester

Chemical Property of H-Lys(Z)-OBzl

Chemical Property:

• Boiling Point: 536.6±50.0 °C(Predicted)
• PKA: 12.67±0.46(Predicted)
• PSA: 90.65000
• Density: 1.163±0.06 g/cm3(Predicted)
• LogP: 4.24500

Purity/Quality:

99% ^*data from raw suppliers

(S)-Benzyl2-amino-6-(((benzyloxy)carbonyl)amino)hexanoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of H-Lys(Z)-OBzl

There total 10 articles about H-Lys(Z)-OBzl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

(S)-6-Benzyloxycarbonylamino-2-[(pyridine-2-carbonyl)-amino]-hexanoic acid benzyl ester → Lys(Z)-OBzl (24458-14-8)

Guidance literature:

With sodium hydroxide; sulfuric acid; In methanol; water; at 25 ℃; pH=2.0, electrochemical reduction;

DOI:10.1016/S0040-4039(97)00362-6

Reference yield:

N-α-tert-Butyloxycarbonyl-N-ε-carbobenzoxy-L-lysine benzyl ester (77236-13-6) → Lys(Z)-OBzl (24458-14-8)

Guidance literature:

With methoxybenzene; trifluoroacetic acid; at 0 ℃; for 0.666667h;

DOI:10.1248/cpb.35.3757

Reference yield:

benzyl alcohol (100-51-6,185532-71-2) → Lys(Z)-OBzl (24458-14-8)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01152a519

upstream raw materials:

N₆-[(benzyloxy)carbonyl]-L-lysine

benzyl alcohol

N-α-tert-Butyloxycarbonyl-N-ε-carbobenzoxy-L-lysine benzyl ester

N,N'-di-[(phenylmethoxy)carbonyl]-L-lysine

Downstream raw materials:

Ts-Lys(Z)-OBzl

Boc-Asn-Lys(Z)-OBzl

N-ε-Carbobenzyloxy-N-α-(indole-3-acetyl)-L-lysine benzyl ester

Boc-Pro-Lys(Z)-OBzl