L-Ribonic acid

Base Information

• Chemical Name: L-Ribonic acid
• CAS No.: 710941-59-6
• Molecular Formula: C5H10 O6
• Molecular Weight: 166.131
• DSSTox Substance ID: DTXSID701317314
• Wikidata: Q27159909
• Mol file: 710941-59-6.mol

Synonyms:L-Ribonic acid;L-(+)-Ribonic acid;710941-59-6;(2S,3S,4S)-2,3,4,5-tetrahydroxypentanoic acid;SCHEMBL16609882;CHEBI:87765;DTXSID701317314;L-Ribonic acid lithium salt, >=95.0% (TLC);Q27159909

Chemical Property of L-Ribonic acid

Chemical Property:

• PSA: 118.22000
• LogP: -2.85400
• XLogP3: -2.7
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 166.04773803
• Heavy Atom Count: 11
• Complexity: 135

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(C(C(=O)O)O)O)O)O
• Isomeric SMILES: C([C@@H]([C@@H]([C@@H](C(=O)O)O)O)O)O

Technology Process of L-Ribonic acid

There total 13 articles about L-Ribonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-arabinose (5328-37-0) → (S)-glyceric acid (473-81-4,600-19-1,6000-40-4,28305-26-2,118916-26-0) + L-erythronic acid (20703-66-6) + L-ribonic acid (710941-59-6) + L-arabinonic acid (608-53-7)

Guidance literature:

With sodium perchlorate; hydroxide; bromamine B; In water; at 30 ℃; for 24h; Further Variations:; Solvents; Kinetics; Thermodynamic data;

DOI:10.1081/CAR-120004334

Reference yield:

C5H8O6 → L-ribonic acid (710941-59-6)

Guidance literature:

With sodium tetrahydroborate; In water; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1055/s-0036-1588857

Reference yield:

(3aS,4S,6R,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxylic acid (54622-95-6) → L-ribonic acid (710941-59-6)

Guidance literature:

Multi-step reaction with 2 steps

1: Amberlyst 15 (H+) / water / 5 h / 70 °C / Inert atmosphere

2: sodium tetrahydroborate / water / 1 h / 0 °C / Inert atmosphere

With sodium tetrahydroborate; In water;

DOI:10.1055/s-0036-1588857

upstream raw materials:

L-arabinose

L-arabinonic acid

L-arabino-1,4-lactone

pyridine

Downstream raw materials:

L-ribono-1,4-lactone

L-ribose

Refernces

• 1、 Ban, Jaeyoung,Shabbir, Saira,Lim, Minkyung,Lee, Byunghoon,Rhee, Hakjune. "Synthesis of l -Ribose from d -Ribose by a Stereoconversion through Sequential Lactonization as the Key Transformation". . p. 4299 - 4302. Retrieved 2017/09/12.