(3S,4S,4aR,6R,7R,8S,8aR,9aS,10R,10aS)-4,10-Bis-benzyloxy-6,7-dimethoxy-3,8-dimethyl-decahydro-1,5,9-trioxa-anthracene

Base Information

Chemical Name:(3S,4S,4aR,6R,7R,8S,8aR,9aS,10R,10aS)-4,10-Bis-benzyloxy-6,7-dimethoxy-3,8-dimethyl-decahydro-1,5,9-trioxa-anthracene
CAS No.:88392-88-5
Molecular Formula:C₂₉H₃₈O₇
Molecular Weight:498.617
Hs Code.:

Synonyms:(3S,4S,4aR,6R,7R,8S,8aR,9aS,10R,10aS)-4,10-Bis-benzyloxy-6,7-dimethoxy-3,8-dimethyl-decahydro-1,5,9-trioxa-anthracene

Suppliers and Price of (3S,4S,4aR,6R,7R,8S,8aR,9aS,10R,10aS)-4,10-Bis-benzyloxy-6,7-dimethoxy-3,8-dimethyl-decahydro-1,5,9-trioxa-anthracene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,4S,4aR,6R,7R,8S,8aR,9aS,10R,10aS)-4,10-Bis-benzyloxy-6,7-dimethoxy-3,8-dimethyl-decahydro-1,5,9-trioxa-anthracene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,4S,4aR,6R,7R,8S,8aR,9aS,10R,10aS)-4,10-Bis-benzyloxy-6,7-dimethoxy-3,8-dimethyl-decahydro-1,5,9-trioxa-anthracene

There total 14 articles about (3S,4S,4aR,6R,7R,8S,8aR,9aS,10R,10aS)-4,10-Bis-benzyloxy-6,7-dimethoxy-3,8-dimethyl-decahydro-1,5,9-trioxa-anthracene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 88392-85-2
(2R,3S,4R,4aR,5S,6S,8aS)-4,5-Bis-benzyloxy-2-((E)-2-[1,3]dioxolan-2-yl-vinyl)-6-methyl-hexahydro-pyrano[2,3-b]pyran-3-ol

: 88392-88-5
(3S,4S,4aR,6R,7R,8S,8aR,9aS,10R,10aS)-4,10-Bis-benzyloxy-6,7-dimethoxy-3,8-dimethyl-decahydro-1,5,9-trioxa-anthracene

Guidance literature:: Multi-step reaction with 5 steps

1: 70 percent / PPTS / 20 h / 20 °C

2: N-bromosuccinimide, H₂O / 1,2-dimethoxy-ethane / 29 h / 20 °C

3: NaH / dimethylformamide / 0.33 h / 20 °C

4: 1.) methyllithium / 1.) ether, THF, 20 deg C, 30 min, 2.) ether, THF, toluene, 80 deg C, 2 h

5: NaH / dimethylformamide

With N-Bromosuccinimide; water; methyllithium; pyridinium p-toluenesulfonate; sodium hydride; In 1,2-dimethoxyethane; N,N-dimethyl-formamide;
DOI:10.1021/jo00229a014

Reference yield:

: 88412-17-3
Acetic acid (2R,3S,4R,4aR,8aS)-3-benzyloxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,4,4a,8a-tetrahydro-2H,7H-pyrano[2,3-b]pyran-4-yl ester

: 88392-88-5
(3S,4S,4aR,6R,7R,8S,8aR,9aS,10R,10aS)-4,10-Bis-benzyloxy-6,7-dimethoxy-3,8-dimethyl-decahydro-1,5,9-trioxa-anthracene

Guidance literature:: Multi-step reaction with 10 steps

1: 91 percent / MCPBA

2: 97 percent

3: 1.) oxidation; 2.) reduction

4: hydrolysis

6: 96 percent / oxidation

8: 86 percent / PPTS / methanol

9: 1.) NBS; 2.) NaH

10: 1.) Me₂Mg; 2.) NaH / 1.) THF

With N-Bromosuccinimide; dimethylmagnesium; pyridinium p-toluenesulfonate; sodium hydride; 3-chloro-benzenecarboperoxoic acid; In methanol;
DOI:10.1021/ja00315a046

Reference yield:

: 88392-82-9
(3aS,4S,6aS,7aR,11aS,11bR,11cR)-2,2,4,10,10-Pentamethyl-octahydro-1,3,6,7,9,11-hexaoxa-benzo[de]anthracene

: 88392-88-5
(3S,4S,4aR,6R,7R,8S,8aR,9aS,10R,10aS)-4,10-Bis-benzyloxy-6,7-dimethoxy-3,8-dimethyl-decahydro-1,5,9-trioxa-anthracene

Guidance literature:: Multi-step reaction with 6 steps

2: 96 percent / oxidation

4: 86 percent / PPTS / methanol

5: 1.) NBS; 2.) NaH

6: 1.) Me₂Mg; 2.) NaH / 1.) THF

With N-Bromosuccinimide; dimethylmagnesium; pyridinium p-toluenesulfonate; sodium hydride; In methanol;
DOI:10.1021/ja00315a046