2,4-Dichlorobenzyl bromide

Base Information

• Chemical Name: 2,4-Dichlorobenzyl bromide
• CAS No.: 20443-99-6
• Molecular Formula: C7H5 Br Cl2
• Molecular Weight: 239.927
• Hs Code.: 2903999090
• European Community (EC) Number: 801-818-8
• DSSTox Substance ID: DTXSID80450963
• Nikkaji Number: J2.224.830H
• Wikidata: Q72465638
• Mol file: 20443-99-6.mol

Synonyms:2,4-dichlorobenzyl bromide;1-(bromomethyl)-2,4-dichlorobenzene;20443-99-6;2,4-dichlorobenzylbromide;BENZENE, 1-(BROMOMETHYL)-2,4-DICHLORO-;MFCD03208523;1-(bromomethyl)-2,4-dichloro-benzene;2,4- Dichlorbenzylbromid;SCHEMBL1137783;DTXSID80450963;RGLQSFFFIREZFV-UHFFFAOYSA-N;1-bromomethyl-2,4-dichlorobenzene;1-bromomethyl-2,4-dichloro-benzene;CK1001;AKOS009307148;AM83116;CS-W021249;AS-17249;D4475;FT-0651513;EN300-54621

Chemical Property of 2,4-Dichlorobenzyl bromide

Chemical Property:

• Vapor Pressure: 0.019mmHg at 25°C
• Melting Point: 32 °C
• Boiling Point: 260.852oC at 760 mmHg
• Flash Point: 126.228oC
• PSA: 0.00000
• Density: 1.68g/cm3
• LogP: 3.88830
• Storage Temp.: 0-10°C
• Solubility.: soluble in Methanol
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 237.89517
• Heavy Atom Count: 10
• Complexity: 108

Purity/Quality:

97% ^*data from raw suppliers

2,4-Dichlorobenzyl Bromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Cl)Cl)CBr

Technology Process of 2,4-Dichlorobenzyl bromide

There total 11 articles about 2,4-Dichlorobenzyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(2,4-dichlorophenyl)methanol (1777-82-8) → 2,4-dichlorobenzyl bromide (20443-99-6)

Guidance literature:

With ethyl 2,2-dibromoacetoacetate; triphenylphosphine; In dichloromethane; at 20 ℃; for 0.25h; Solvent; Reagent/catalyst;

DOI:10.1016/j.tetlet.2013.10.120

Reference yield: 98.0%

2,4-dichlorobenzaldeyhde (874-42-0) → 2,4-dichlorobenzyl bromide (20443-99-6)

Guidance literature:

With polymethylhydrosiloxane; dimethylbromosulphonium bromide; In chloroform; at 20 ℃; for 4h;

DOI:10.1016/j.tetlet.2007.07.125

Reference yield: 91.0%

→ 2,4-dichlorobenzyl bromide (20443-99-6)

Guidance literature:

With hydrogen bromide; In water; at 120 ℃; for 2h;

upstream raw materials:

2,4-dichlorotoluene

(2,4-dichlorophenyl)methanol

2,4-dichlorobenzaldeyhde

2,4-dichloro-1-(methoxymethoxy)methyl benzene

Downstream raw materials:

2,4-Dichlorophenylacetonitrile

ethyl 1-[(5-bromo-2-{[(2,4-dichlorophenyl)methyl]oxy}phenyl)methyl]-5-methyl-1H-pyrazole-3-carboxylate

5-(4-chlorophenyl)-6-[4-(methylthio)phenyl]-2-(2,4-dichlorobenzyl)-2H-pyridazin-3-one

(1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentan-1-yl]-6-(2,4-dichloro-benzylthio)purine