2,3-Dimethoxybenzyl chloride

Base Information

• Chemical Name: 2,3-Dimethoxybenzyl chloride
• CAS No.: 3893-01-4
• Molecular Formula: C9H11ClO2
• Molecular Weight: 186.638
• Hs Code.: 2909309090
• European Community (EC) Number: 674-292-9
• DSSTox Substance ID: DTXSID90374303
• Nikkaji Number: J1.157.287A
• Wikidata: Q72467751
• Mol file: 3893-01-4.mol

Synonyms:2,3-dimethoxybenzyl chloride;1-(chloromethyl)-2,3-dimethoxybenzene;3893-01-4;Benzene, 1-(chloromethyl)-2,3-dimethoxy-;2, 3-dimethoxybenzyl chloride;SCHEMBL2500056;DTXSID90374303;MJRVJLUCLPUZER-UHFFFAOYSA-N;2,3-DIMETHOXYBENZYLCHLORIDE;3-chloromethyl-1,2-dimethoxybenzene;MFCD01310812;1-chloromethyl-2,3-dimethoxy-benzene;AKOS000262341;BS-28043;FT-0635051;EN300-1263303;2,3-Dimethoxybenzyl chloride 50% in Methylene chloride

Chemical Property of 2,3-Dimethoxybenzyl chloride

Chemical Property:

• Vapor Pressure: 0.038mmHg at 25°C
• Melting Point: 69-70.5℃
• Refractive Index: 1.509
• Boiling Point: 248.6 °C at 760 mmHg
• Flash Point: 89.3 °C
• PSA: 18.46000
• Density: 1.13g/cm³
• LogP: 2.44260
• Storage Temp.: Keep Cold
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 186.0447573
• Heavy Atom Count: 12
• Complexity: 130

Purity/Quality:

97% ^*data from raw suppliers

2,3-Dimethoxybenzyl chloride (50% by weight in methylene chloride) 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=CC(=C1OC)CCl

Technology Process of 2,3-Dimethoxybenzyl chloride

There total 5 articles about 2,3-Dimethoxybenzyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%

→ 2,3-dimethoxybenzyl chloride (3893-01-4)

Guidance literature:

Reference yield: 99.0%

2,3-dimethoxybenzyl alcohol (5653-67-8) → 2,3-dimethoxybenzyl chloride (3893-01-4)

Guidance literature:

With thionyl chloride; In benzene; for 1.5h;

DOI:10.1139/v82-385

Reference yield:

2,6-dimethylpyridine (108-48-5) + 2,3-dimethoxybenzyl alcohol (5653-67-8) → 2,3-dimethoxybenzyl chloride (3893-01-4) + 4-chloromethyl-1,2-dimethoxy-benzene (7306-46-9)

Guidance literature:

With thionyl chloride; In dichloromethane;

upstream raw materials:

2,3-dimethoxybenzyl alcohol

2,3-dimethyoxybenzaldehyde

2,6-dimethylpyridine

Downstream raw materials:

N,N-dimethyl-2,3-dimethoxybenzylamine

1,2-bis-chloromethyl-3,4-dimethoxy-benzene

octacosane

1,2-dimethoxy-3-pentadecyl-benzene