(1S,2R)-2-[(S)-2-(4-Methoxy-phenoxy)-1-methyl-ethyl]-cyclopentanecarboxylic acid methyl ester

Base Information

• Chemical Name: (1S,2R)-2-[(S)-2-(4-Methoxy-phenoxy)-1-methyl-ethyl]-cyclopentanecarboxylic acid methyl ester
• CAS No.: 228262-79-1
• Molecular Formula: C₁₇H₂₄O₄
• Molecular Weight: 292.375

Synonyms:(1S,2R)-2-[(S)-2-(4-Methoxy-phenoxy)-1-methyl-ethyl]-cyclopentanecarboxylic acid methyl ester

Chemical Property of (1S,2R)-2-[(S)-2-(4-Methoxy-phenoxy)-1-methyl-ethyl]-cyclopentanecarboxylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,2R)-2-[(S)-2-(4-Methoxy-phenoxy)-1-methyl-ethyl]-cyclopentanecarboxylic acid methyl ester

There total 2 articles about (1S,2R)-2-[(S)-2-(4-Methoxy-phenoxy)-1-methyl-ethyl]-cyclopentanecarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4-methoxy-phenol (150-76-5) + (1S,2R)-2-((S)-2-Hydroxy-1-methyl-ethyl)-cyclopentanecarboxylic acid methyl ester (228262-78-0) → (1S,2R)-2-[(S)-2-(4-Methoxy-phenoxy)-1-methyl-ethyl]-cyclopentanecarboxylic acid methyl ester (228262-79-1)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 80 ℃; for 2h;

DOI:10.1016/S0040-4039(99)00578-X

Reference yield:

(1S,2R)-2-((S)-1-Methyl-2-oxo-ethyl)-cyclopentanecarboxylic acid methyl ester (228262-77-9) → (1S,2R)-2-[(S)-2-(4-Methoxy-phenoxy)-1-methyl-ethyl]-cyclopentanecarboxylic acid methyl ester (228262-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / NaBH₄ / methanol / 1 h / 0 °C

2: 93 percent / PPh₃, diethyl azodicarboxylate / tetrahydrofuran / 2 h / 80 °C

With sodium tetrahydroborate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol;

DOI:10.1016/S0040-4039(99)00578-X

Reference yield: 69.0%

prenyl bromide (870-63-3) + (1S,2R)-2-[(S)-2-(4-Methoxy-phenoxy)-1-methyl-ethyl]-cyclopentanecarboxylic acid methyl ester (228262-79-1) → (1S,2R)-2-[(S)-2-(4-Methoxy-phenoxy)-1-methyl-ethyl]-1-(3-methyl-but-2-enyl)-cyclopentanecarboxylic acid methyl ester (228262-80-4)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; -78 deg C to RT, 22 h;

DOI:10.1016/S0040-4039(99)00578-X

upstream raw materials:

4-methoxy-phenol

(1S,2R)-2-((S)-2-Hydroxy-1-methyl-ethyl)-cyclopentanecarboxylic acid methyl ester

(1S,2R)-2-((S)-1-Methyl-2-oxo-ethyl)-cyclopentanecarboxylic acid methyl ester

Downstream raw materials:

(1S,2R)-2-[(S)-2-(4-Methoxy-phenoxy)-1-methyl-ethyl]-1-(3-methyl-but-2-enyl)-cyclopentanecarboxylic acid methyl ester

1-{(S)-2-[(1R,2S)-2-Isocyanato-2-(3-methyl-but-2-enyl)-cyclopentyl]-propoxy}-4-methoxy-benzene

(1S,2R)-2-[(S)-2-(4-Methoxy-phenoxy)-1-methyl-ethyl]-1-(3-methyl-but-2-enyl)-cyclopentanecarboxylic acid

[(1S,2R)-2-[(S)-2-(4-Methoxy-phenoxy)-1-methyl-ethyl]-1-(3-methyl-but-2-enyl)-cyclopentyl]-carbamic acid benzyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 228262-79-1 (1S,2R)-2-[(S)-2-(4-Methoxy-phenoxy)-1-methyl-ethyl]-cyclopentanecarboxylic acid methyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send