Fmoc-3-aminotyrosine allyl ester

Base Information

• Chemical Name: Fmoc-3-aminotyrosine allyl ester
• CAS No.: 1414878-87-7
• Molecular Formula: C₂₇H₂₆N₂O₅
• Molecular Weight: 458.514
• Mol file: 1414878-87-7.mol

Synonyms:Fmoc-3-aminotyrosine allyl ester

Chemical Property of Fmoc-3-aminotyrosine allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Fmoc-3-aminotyrosine allyl ester

There total 3 articles about Fmoc-3-aminotyrosine allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

Fmoc-3-nitrotyrosine allyl ester (1414878-81-1) → Fmoc-3-aminotyrosine allyl ester (1414878-87-7)

Guidance literature:

With acetic acid; zinc; In methanol; at 50 ℃; for 1h;

Reference yield:

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide (82911-69-1) → Fmoc-3-aminotyrosine allyl ester (1414878-87-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N-ethyl-N,N-diisopropylamine / 1,4-dioxane; water / pH 8.5

1.3: 0 - 20 °C

2.1: zinc; acetic acid / methanol / 1 h / 50 °C

With acetic acid; N-ethyl-N,N-diisopropylamine; zinc; In 1,4-dioxane; methanol; water;

Reference yield:

3-nitrotyrosine nitrate (133541-26-1) → Fmoc-3-aminotyrosine allyl ester (1414878-87-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N-ethyl-N,N-diisopropylamine / 1,4-dioxane; water / pH 8.5

1.3: 0 - 20 °C

2.1: zinc; acetic acid / methanol / 1 h / 50 °C

With acetic acid; N-ethyl-N,N-diisopropylamine; zinc; In 1,4-dioxane; methanol; water;

upstream raw materials:

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

Fmoc-3-nitrotyrosine allyl ester

3-nitrotyrosine nitrate

Downstream raw materials:

Fmoc-3-azidotyrosine allyl ester

Fmoc-3-azido-O-(dibenzylphosphoryl)tyrosine allyl ester

Fmoc-3-azido-O-(dibenzylphosphoryl)tyrosine