Technology Process of C21H36O3Si
There total 5 articles about C21H36O3Si which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(S)-7-((tert-butyldimethylsilyl)oxy)hept-1-en-3-ol;
With
sodium hydride;
In
N,N-dimethyl-formamide; mineral oil;
at 0 ℃;
for 0.333333h;
p-Methoxybenzyl bromide;
In
N,N-dimethyl-formamide; mineral oil;
at 0 - 20 ℃;
for 1h;
DOI:10.1002/asia.201100429
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride / tetrahydrofuran / 3 h / 20 °C
2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -78 °C
2.2: 20 °C
3.1: tetrahydrofuran / 5 h / 0 - 20 °C
3.2: 96 h / -22 °C / Molecular sieve; Resolution of racemate
4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.33 h / 0 °C
4.2: 1 h / 0 - 20 °C
With
oxalyl dichloride; sodium hydride; dimethyl sulfoxide;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; mineral oil;
2.1: Swern oxidation / 2.2: Swern oxidation;
DOI:10.1002/asia.201100429
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tetrahydrofuran / 5 h / 0 - 20 °C
1.2: 96 h / -22 °C / Molecular sieve; Resolution of racemate
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.33 h / 0 °C
2.2: 1 h / 0 - 20 °C
With
sodium hydride;
In
tetrahydrofuran; N,N-dimethyl-formamide; mineral oil;
DOI:10.1002/asia.201100429
