87184-80-3 Usage
General Description
5-[(tert-Butyldimethylsilyl)oxy]pentanal is a chemical compound with the molecular formula C12H26O2Si. It is a silyl enol ether, which is commonly used in organic synthesis as a protecting group for aldehydes and ketones. The tert-butyldimethylsilyl (TBS) group provides protection for the aldehyde functional group, preventing unwanted reactions or side reactions during subsequent chemical reactions. 5-[(tert-Butyldimethylsilyl)oxy]pentanal is commonly used in the production of pharmaceuticals and agrochemicals, as well as in the synthesis of complex natural products. The TBS protecting group can also be easily removed under mild conditions, making it a versatile and valuable tool in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 87184-80-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,1,8 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 87184-80:
(7*8)+(6*7)+(5*1)+(4*8)+(3*4)+(2*8)+(1*0)=163
163 % 10 = 3
So 87184-80-3 is a valid CAS Registry Number.
87184-80-3Relevant articles and documents
Aromatization of 2,2,5-trialkyl-substituted 2,5-dihydrofurans and factors affecting their stabilization
Sharipov, Bulat T.,Davidova, Anna N.,Valeev, Farid A.
, p. 403 - 410 (2018/06/11)
[Figure not available: see fulltext.] We demonstrate that the synthesis of 5-methoxy-2,2,5-trialkyl-substituted 2,5-dihydrofurans containing unprotected hydroxymethyl group at the C-2 position involves aromatization via fragmentation involving С–С bond cleavage, resulting in the formation of 2,5-disubstituted furans and carbonyl compounds. 2,5-Dihydrofurans bearing an ester group at the С-2 position were stable. It was found that 2,2,5-trialkyl-substituted 2,5-dihydrofurans containing a hydroxymethyl or carbonyl group in the side chain could aromatize through auto-oxidation, which was facilitated by adjacent functional groups (sulfo- or pivaloyl groups).
