87184-80-3 Usage
Uses
Used in Pharmaceutical Industry:
5-[(tert-Butyldimethylsilyl)oxy]pentanal is used as a protecting group for aldehydes and ketones in the synthesis of pharmaceuticals. The TBS group provides protection for the aldehyde functional group, allowing for selective reactions and preventing unwanted side reactions. This ensures the purity and yield of the final product, contributing to the development of effective and safe medications.
Used in Agrochemical Industry:
5-[(tert-Butyldimethylsilyl)oxy]pentanal is used as a protecting group in the synthesis of agrochemicals. The TBS group protects the aldehyde functional group, enabling selective reactions and avoiding side reactions that could lead to impurities or reduced yields. This ensures the production of high-quality agrochemicals with desired properties and minimal environmental impact.
Used in Synthesis of Complex Natural Products:
5-[(tert-Butyldimethylsilyl)oxy]pentanal is used as a protecting group in the synthesis of complex natural products. The TBS group shields the aldehyde functional group, allowing for selective reactions and preventing side reactions that could complicate the synthesis process. This facilitates the production of complex natural products with high purity and yield, contributing to the development of novel therapeutic agents and other applications.
Used in Organic Synthesis:
5-[(tert-Butyldimethylsilyl)oxy]pentanal is used as a versatile protecting group in various organic synthesis applications. The TBS group provides protection for the aldehyde functional group, enabling selective reactions and preventing unwanted side reactions. The mild conditions required for the removal of the TBS group make it a valuable tool for chemists, allowing for the synthesis of a wide range of organic compounds with high purity and yield.
Check Digit Verification of cas no
The CAS Registry Mumber 87184-80-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,1,8 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 87184-80:
(7*8)+(6*7)+(5*1)+(4*8)+(3*4)+(2*8)+(1*0)=163
163 % 10 = 3
So 87184-80-3 is a valid CAS Registry Number.
87184-80-3Relevant academic research and scientific papers
Aromatization of 2,2,5-trialkyl-substituted 2,5-dihydrofurans and factors affecting their stabilization
Sharipov, Bulat T.,Davidova, Anna N.,Valeev, Farid A.
, p. 403 - 410 (2018/06/11)
[Figure not available: see fulltext.] We demonstrate that the synthesis of 5-methoxy-2,2,5-trialkyl-substituted 2,5-dihydrofurans containing unprotected hydroxymethyl group at the C-2 position involves aromatization via fragmentation involving С–С bond cleavage, resulting in the formation of 2,5-disubstituted furans and carbonyl compounds. 2,5-Dihydrofurans bearing an ester group at the С-2 position were stable. It was found that 2,2,5-trialkyl-substituted 2,5-dihydrofurans containing a hydroxymethyl or carbonyl group in the side chain could aromatize through auto-oxidation, which was facilitated by adjacent functional groups (sulfo- or pivaloyl groups).
