prop-2-enyl 3-{[3-(4-hydroxyphenyl)-4-oxo-3-hydroquinazolin-7-yloxy]methyl} benzoate

Base Information

Chemical Name:prop-2-enyl 3-{[3-(4-hydroxyphenyl)-4-oxo-3-hydroquinazolin-7-yloxy]methyl} benzoate
CAS No.:1068437-11-5
Molecular Formula:C₂₅H₂₀N₂O₅
Molecular Weight:428.444
Hs Code.:

Synonyms:prop-2-enyl 3-{[3-(4-hydroxyphenyl)-4-oxo-3-hydroquinazolin-7-yloxy]methyl} benzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of prop-2-enyl 3-{[3-(4-hydroxyphenyl)-4-oxo-3-hydroquinazolin-7-yloxy]methyl} benzoate

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Technology Process of prop-2-enyl 3-{[3-(4-hydroxyphenyl)-4-oxo-3-hydroquinazolin-7-yloxy]methyl} benzoate

There total 2 articles about prop-2-enyl 3-{[3-(4-hydroxyphenyl)-4-oxo-3-hydroquinazolin-7-yloxy]methyl} benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 887468-70-4
7-hydroxy-3-(4-hydroxyphenyl)-3-hydroquinazolin-4-one

: 225122-54-3
3-chloromethyl-benzoic acid allyl ester

: 1068437-11-5
prop-2-enyl 3-{[3-(4-hydroxyphenyl)-4-oxo-3-hydroquinazolin-7-yloxy]methyl} benzoate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 4.5h;

Reference yield:

: 880450-36-2
7-methoxy-3-(4-methoxyphenyl)-3-hydroquinazolin-4-one

: 1068437-11-5
prop-2-enyl 3-{[3-(4-hydroxyphenyl)-4-oxo-3-hydroquinazolin-7-yloxy]methyl} benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: boron tribromide / dichloromethane / 264.5 h / 0 - 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 4.5 h / 80 °C

With boron tribromide; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;