<2S-(1E,2α,3α,5α)>-<3-(Acetyloxy)-2-<<(2,2,2-trichloroethoxy)carbonyl>oxy>-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylcyclohexylidene>acetic Acid Ethyl Ester

Base Information

Chemical Name:<2S-(1E,2α,3α,5α)>-<3-(Acetyloxy)-2-<<(2,2,2-trichloroethoxy)carbonyl>oxy>-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylcyclohexylidene>acetic Acid Ethyl Ester
CAS No.:123836-56-6
Molecular Formula:C₂₂H₃₅Cl₃O₈Si
Molecular Weight:561.96
Hs Code.:

<2S-(1E,2α,3α,5α)>-<3-(Acetyloxy)-2-<<(2,2,2-trichloroethoxy)carbonyl>oxy>-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylcyclohexylidene>acetic Acid Ethyl Ester

Synonyms:<2S-(1E,2α,3α,5α)>-<3-(Acetyloxy)-2-<<(2,2,2-trichloroethoxy)carbonyl>oxy>-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylcyclohexylidene>acetic Acid Ethyl Ester

Suppliers and Price of <2S-(1E,2α,3α,5α)>-<3-(Acetyloxy)-2-<<(2,2,2-trichloroethoxy)carbonyl>oxy>-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylcyclohexylidene>acetic Acid Ethyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of <2S-(1E,2α,3α,5α)>-<3-(Acetyloxy)-2-<<(2,2,2-trichloroethoxy)carbonyl>oxy>-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylcyclohexylidene>acetic Acid Ethyl Ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of <2S-(1E,2α,3α,5α)>-<3-(Acetyloxy)-2-<<(2,2,2-trichloroethoxy)carbonyl>oxy>-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylcyclohexylidene>acetic Acid Ethyl Ester

There total 6 articles about <2S-(1E,2α,3α,5α)>-<3-(Acetyloxy)-2-<<(2,2,2-trichloroethoxy)carbonyl>oxy>-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylcyclohexylidene>acetic Acid Ethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 123836-55-5
<2S-(1E,2α,3α,5α)>-<3-(Acetyloxy)-2-<<(2,2,2-trichloroethoxy)carbonyl>oxy>-5-hydroxy-2-methylcyclohexylidene>acetic Acid Ethyl Ester

: 18162-48-6
tert-butyldimethylsilyl chloride

: 123836-56-6
<2S-(1E,2α,3α,5α)>-<3-(Acetyloxy)-2-<<(2,2,2-trichloroethoxy)carbonyl>oxy>-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylcyclohexylidene>acetic Acid Ethyl Ester

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; for 18h; Ambient temperature;
DOI:10.1021/jo00288a040

Reference yield:

: 123836-51-1
<2S-(1E,2α,3α,5α)>-<3-(Acetyloxy)-2-hydroxy-2-methyl-5-(1-methylethenyl)cyclohexylidene>acetic Acid Ethyl Ester

: 123836-56-6
<2S-(1E,2α,3α,5α)>-<3-(Acetyloxy)-2-<<(2,2,2-trichloroethoxy)carbonyl>oxy>-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylcyclohexylidene>acetic Acid Ethyl Ester

Guidance literature:: Multi-step reaction with 5 steps

1: 100 percent / 4-(dimethylamino)pyridine / pyridine / 72 h / 25 °C

2: 83 percent / 1percent aq. OsO₄, potassium periodate / tetrahydrofuran; H₂O / 31 h / 25 °C

3: 93 percent / 90percent H₂O₂, trifluoracetic anhydride, KH₂PO₄ / CH₂Cl₂ / 23 h / 0 °C

4: 58 percent / cation-exchange resin AG 50W-X₄ / ethanol / 21 h / 25 °C

5: 96 percent / imidazole / dimethylformamide / 18 h / Ambient temperature

With 1H-imidazole; dmap; potassium dihydrogenphosphate; osmium(VIII) oxide; potassium metaperiodate; cation-exchange resin AG 50W-X₄; dihydrogen peroxide; trifluoroacetic anhydride; In tetrahydrofuran; pyridine; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jo00288a040

Reference yield:

: 81506-17-4
<2S-(1E,2α,3β,5α)>-<2-(acetyloxy)-3-hydroxy-2-methyl-5-(1-methylethenyl)cyclohexylidene>acetic acid ethyl ester

: 123836-56-6
<2S-(1E,2α,3α,5α)>-<3-(Acetyloxy)-2-<<(2,2,2-trichloroethoxy)carbonyl>oxy>-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylcyclohexylidene>acetic Acid Ethyl Ester

Guidance literature:: Multi-step reaction with 6 steps

1: 86 percent / (diethylamido)sulfur trifluoride / CH₂Cl₂ / 1.)-75 deg C, 1.5 h, 2.)0 deg C, 1.5 h

2: 100 percent / 4-(dimethylamino)pyridine / pyridine / 72 h / 25 °C

3: 83 percent / 1percent aq. OsO₄, potassium periodate / tetrahydrofuran; H₂O / 31 h / 25 °C

4: 93 percent / 90percent H₂O₂, trifluoracetic anhydride, KH₂PO₄ / CH₂Cl₂ / 23 h / 0 °C

5: 58 percent / cation-exchange resin AG 50W-X₄ / ethanol / 21 h / 25 °C

6: 96 percent / imidazole / dimethylformamide / 18 h / Ambient temperature

With 1H-imidazole; dmap; potassium dihydrogenphosphate; osmium(VIII) oxide; potassium metaperiodate; (diethylamido)sulfur trifluoride; cation-exchange resin AG 50W-X₄; dihydrogen peroxide; trifluoroacetic anhydride; In tetrahydrofuran; pyridine; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jo00288a040